2012年9月1日 · Transcranial B-mode sonography (TCS) is a neuroimaging technique that displays the brain parenchyma and the intracranial ventricular system through the intact skull. Sophisticated TCS systems can currently achieve a higher image resolution of echogenic deep brain structures than MRI under clinical conditions.

2023年7月10日 · 从Becker首次描述PD患者黑质回声增强（substantia nigra hyperechogenicity，SN+）以来，国内外大量研究报道经颅超声（TCS）可作为PD影像学标志物之一，为PD早期诊断提供辅助证据，并协助鉴别其他运动障碍性疾病。现对TCS在PD临床诊断中的研究进展作一综述。

The transcranial sonographic findings of SN differ between patients with PD and those with other dyskinesia diseases. For example, the main characteristic of PD in transcranial sonography (TCS) is SN hyperechogenicity, while some forms of AP may be characterized by hyperechogenicity of the nucleus lentiformis . Therefore, TCS of the SN may be ...

2007年1月1日 · TCS of distinct infra- and supratentorial brain structures detects characteristic changes in several movement disorders, such as abnormal hyperechogenicity of substantia nigra (SN) in Parkinson’s disease and of lenticular nucleus in dystonia, Wilson’s disease and atypical Parkinsonian disorders.

The present study confirmed that TCS of the SN is potentially useful in the investigation of Japanese patients, and it provides a better differential diagnosis between PD and atypical parkinsonism. The recording failure of TCS in aged, particularly female subjects, may limit the clinical potential o …

This study demonstrated that the TCS-derived feature of SN positivity could effectively differentiate PD from ET, PSP, and MSA in a Chinese population. Furthermore, the incidence of lenticular hyperechoic areas is relatively low in PD and in other movement disorders in our study.

2012年12月26日 · Accumulating evidence suggested that olfactory dysfunction, substantia nigra (SN) hyperechogenicity on transcranial sonography (TCS) might be risk markers of PD [2, 3], which was helpful for making early and differential diagnosis.

2010年4月16日 · Transcranial sonography (TCS) of the substantia nigra (SN) is used as a clinical screen for Parkinson disease (PD) because the SN is enlarged in approximately 90% of PD patients. Because ADHD and PD have similarities in frontostriatal dopaminergic pathways, these researchers studied TCS of the SN in 29 children with diagnosed or suspected ADHD ...

2010年1月21日 · Our study shows that TCS is a reliable and highly sensitive tool for differentiation of IPD patients from individuals without CNS disorders. Diagnosis of idiopathic Parkinson's disease (IPD) is usually based on clinical criteria. However, in some cases differential diagnosis especially in early stages of the disease might be difficult.

Transcranial sonography (TCS) shows an increased echogenic area of the substantia nigra (SN) in patients with Parkinson disease (PD). It has been increasingly used in the diagnosis of PD and its differentiation from atypical parkinsonian syndromes. …