2015年6月7日 · MDR-TB is defined as resistance to isoniazid and rifampicin, with or without resistance to other first-line drugs (FLD). XDR-TB is defined as resistance to at least isoniazid …

Totally drug-resistant tuberculosis (TDR-TB) is a generic term for tuberculosis strains that are resistant to a wider range of drugs than strains classified as extensively drug-resistant …

In 2009, we proposed the term “Totally Drug–Resistant Tuberculosis (TDR-TB) “for TB strains that showed in-vitro resistance to all first and second line drugs tested (isoniazid, rifampicin, …

2023年12月21日 · Multidrug-resistant TB disease (MDR TB) is caused by germs that are resistant to two or more of the main TB medicines: isoniazid and rifampin. Two more serious forms of …

2021年2月1日 · In this review, we present the molecular mechanisms behind Mycobacterium tolerance to drugs and their approach towards the development of multi-drug resistant, …

2025年1月6日 · Drug-resistant tuberculosis (TB) disease is caused by TB bacteria that are resistant to at least one of the most effective TB medicines used in treatment regimens. Drug …

XDR-TB是广泛耐药结核病的缩写。 它是一种由结核分枝杆菌复合群菌株引起的结核病，该菌株对利福平耐药（也可能对异烟肼有耐药性），并且对至少一种氟喹诺酮类药物（左氧氟沙星或莫 …

While the mechanism of resistance proceeds further, it ultimately causes unmanageable totally drug resistant TB (TDR-TB). Studying the molecular mechanisms underlying the resistance to …

Totally drug-resistant tuberculosis (TDR-TB): A debate on global health communities Int J Mycobacteriol . 2013 Jun;2(2):71-2. doi: 10.1016/j.ijmyco.2013.04.005.

In this review we mainly focused on molecular targets containing mutations which are found to be involved in development of drug resistance in M. tuberculosis. WHO identified that TB is …