Tet methylcytosine dioxygenase 2 - Wikipedia
TET2 encodes a protein that catalyzes the conversion of the modified DNA base methylcytosine to 5-hydroxymethylcytosine. The first mechanistic reports showed tissue-specific accumulation …
TET蛋白 - 百度百科
TET（ten-eleven translocation）蛋白是生物体内存在的一种 α-酮戊二酸 （α-KG）和Fe 2+ 依赖的双加氧酶，在靠近C的一端拥有一个催化 结构域，该结构域具有3个金属离子（Fe 2+）和1 …
TET2 Gene - GeneCards | TET2 Protein | TET2 Antibody
2024年12月25日 · TET2 (Tet Methylcytosine Dioxygenase 2) is a Protein Coding gene. Diseases associated with TET2 include Immunodeficiency 75 With Lymphoproliferation and …
TET2基因突变在髓系肿瘤中的研究进展 - 中国医学科学 ...
tet2为tet家族成员之一,是一个与造血系统发育密切相关的肿瘤抑制基因。 近年研究发现,TET2通过将DNA上的5-甲基胞嘧啶(5-mc)氧化为5-羟甲基胞嘧啶(5-hmc),参与DNA的去甲基化过程。
曹雪涛组Nature揭示TET2参与基因表达转录后调控的新模式 - 知乎
研究人员利用紫外交联免疫共沉淀结合高通量测序（CLIP-seq）和单个核苷酸分辨率的全转录组RNA甲基化测序等RNA相关组学技术，发现TET2可通过其酶活作用于Scoc3 mRNA的3’-UTR …
TET2 deficiency increases the competitive advantage of …
2025年3月10日 · Briefly, Tet2 WT or Tet2 KO cells were seeded at a density of 2x10 5 cells/mL in a well in a 24-well TC-treated tissue culture plate (Falcon, #353047) and infected with 50uL of …
TET2 tet methylcytosine dioxygenase 2 [ (human)] - National …
2025年2月8日 · TET2 inhibits the proliferation and metastasis of lung adenocarcinoma cells via activation of the cGAS-STING signalling pathway. Nuclear localization of TET2 requires beta …
TET2 chemically modifies tRNAs and regulates tRNA fragment levels - Nature
2020年11月23日 · TET2 promotes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine on tRNAs and affects the processing or stability of different classes of tRNA fragments.
Cell Reports丨复旦团队揭示TET2调控DNA 损伤应激新机制 - 知乎
TET 家族 5-甲基胞嘧啶 羟化酶包括了TET1、 TET2 和TET3，催化DNA 5位甲基胞嘧啶（5mC）的三步氧化反应，最终实现去甲基化的胞嘧啶的去甲基化过程，在基因组 表观遗传 …
TET2 gene - MedlinePlus
The TET2 gene provides instructions for making a protein whose function is unknown. Based on the function of similar proteins, researchers believe the TET2 protein is involved in regulating …