TGF-β-induced alternative splicing of TAK1 promotes EMT and …
2019年1月9日 · TGF-β-activated kinase 1 (TAK1), also known as MAPK kinase kinase 7, is one of the best characterized non-Smad signal transducers critical for TGF-β functions in EMT and...
转化生长因子激酶1（TAK1）｜ELISA指标 - 百家号
2024年11月13日 · 转化生长因子激酶1（TAK1），也被称为TGF-β-活化蛋白激酶1（Transforming Growth Factor-β-Activated Kinase 1）或有丝分裂原激活蛋白激酶激酶7（MAP3K7），是一种 …
TAK1-TABs Complex: A Central Signalosome in Inflammatory Responses
2021年1月5日 · Transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) is a member of the MAPK kinase kinase (MAPKKK) family and has been implicated in the regulation of a wide …
TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 …
2013年3月21日 · TAK1 enhances TGF-β-induced NF-κB activation, as TAK1 siRNA knockdown decreased TGF-β1-induced phosphorylation of IKK, IκB and RELA, degradation of IκBα, RELA …
Transforming growth factor (TGF)-β-activated kinase 1 (TAK1
2014年8月29日 · TGF-β-activated kinase 1 (TAK1) is a key kinase in mediating Toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R) signaling. Although TAK1 activation involves the …
The type I TGF-β receptor engages TRAF6 to activate TAK1 in a
2008年8月31日 · Our data show that TGF-β specifically activates TAK1 through interaction of TβRI with TRAF6, whereas activation of Smad2 is not dependent on TRAF6. TβRII and TβRI …
转化生长因子激酶1（TAK1）|ELISA指标 - 知乎 - 知乎专栏
转化生长因子激酶1 （TAK1），也被称为TGF-β-活化蛋白激酶1（Transforming Growth Factor-β-Activated Kinase 1）或有丝分裂原激活蛋白激酶激酶7（MAP3K7），是一种重要的信号传导蛋 …
TGF-β signaling via TAK1 pathway: Role in kidney fibrosis
In this review, we focus on current insights into the mechanism and function of Smad-independent signaling pathway via TGF-β-activated kinase 1 (TAK1) and its role in mediating the profibrotic …
TAK1 activation of alpha-TAT1 and microtubule hyperacetylation …
2018年4月27日 · Here we report TGF-β-activated kinase 1 (TAK1) as a key activator of αTAT1. TAK1 directly interacts with and phosphorylates αTAT1 at Ser237 to critically enhance its …
TAK1-TABs复合体：炎症反应中的中央信号体。,Frontiers in …
转化生长因子-β（TGF-β）激活的激酶1（TAK1）是MAPK激酶激酶（MAPKKK）家族的成员，并已参与多种生理和病理过程的调控。 TAK1通过与其结合伴侣TAK1结合蛋白（TAB1，TAB2 …