The TIF 2.0 procedures helps to lengthen, strengthen, and tighten the lower esophageal sphincter by creating a 3 cm 270° esophagogastric fundoplication. For patients who need a repair of the diaphragmatic crura, TIF 2.0 can be performed consecutively with a hiatal hernia repair (greater than 2cm), in the same anesthesia setting.

2024年2月4日 · Optimized TIF 2.0: >300-degree TIF circumference and >3-cm length; standard TIF: ≤300-degree circumference or ≤3-cm length. Only 2 sites routinely performed post-TIF pH testing (on 40 patients [87%]), and other sites had follow-up Bravo in 0% to 4% of patients; overall 46/85 patients (54%) had routine pH testing.

In this study, clinical outcomes were evaluated at 5 years post-TIF 2.0. Methods: A total of 63 chronic gastroesophageal reflux disease (GERD) sufferers with troublesome symptoms refractory to proton pump inhibitor (PPI) therapy, absent or ≤2 cm hiatal hernia, and abnormal esophageal acid exposure were randomized to the TIF group or PPI group.

TIF 2.0 not only creates a larger rotational wrap, but it creates a greater length of valve below the diaphragm. One of the main principles of antireflux surgery is the creation of a valve that is at least 2 to 4 cm, and TIF 2.0 accomplishes this.

Esophageal AET was normal in 72%, greater with an optimized TIF 2.0 valve (defined as >300-degree circumference and >3-cm length; 94% vs 57%; P = .007). There were no TIF 2.0-related serious adverse events. Conclusions: TIF 2.0 is a safe and effective endoscopic outpatient treatment option for selected patients with GERD.

Transoral incisionless fundoplication (TIF) is an endo-scopic procedure that creates a partial esophagogastric fundoplication for selected nonobese patients with hiatal hernias <2 cm.8 Accumulated evidence, including sham-controlled and randomized controlled trials comparing PPI and TIF 2.0, show favorable clinical outcomes and low rate of AEs.10

The TIF 2.0 procedure with the EsophyX® device uses an incisionless approach to treat the underlying anatomical cause of gastroesophageal reflux disease (GERD) — a chronic condition caused by changes in the gastroesophageal valve (GEV) that allow acid to flow back from the stomach into the esophagus.

The TIF procedure has emerged as an endoscopic treatment for patients with refractory gastro-esophageal reflux disease (GERD). Previous systematic reviews of the TIF procedure conflated findings from studies with modalities that do not reflect the current 2.0 procedure technique or refined data-back …

2020年9月15日 · The TIF 2.0 procedure enables an incisionless approach to fundoplication in which a device is inserted through the mouth, down the esophagus and into the upper portion of the stomach. This approach offers patients looking for an alternative to traditional surgery an effective treatment option to correct the underlying cause of GERD.

2024年5月19日 · Surgical options have emerged and constantly developed until the most recent transoral incisionless fundoplication 2.0 (TIF2.0) procedure, which has been shown to improve symptoms, medication cessation, and high safety profile. However, there is little data on adverse events associated with the device employed in this procedure.