2022年6月1日 · Eu 3+ @ 1 and Eu 3+ @ 2 in aqueous solution can achieve the quantitative detection of 2, 4, 6-trinitrobenzene (TNP), tetracycline (TC) and pesticides with high sensitivity and selectivity. In particular, when the volume of TNP increases to 50 μL, the luminescence quenching rate of Eu 3+ @ 2 can reach 99.7% and the LOD for TNP can reach 78 nM.

水溶液中的Eu 3+ @ 1和Eu 3+ @ 2可以实现对2, 4, 6-三硝基苯(TNP)、四环素(TC)和农药的定量检测，具有高灵敏度和高选择性。 特别是当TNP的体积增加到50 μL时，Eu 3+ @ 2的发光猝灭率可以达到99.7%，TNP的LOD可以达到78 nM。

在用于tnp检测的众多技术中，基于不同功能材料的荧光策略以其灵敏度和选择性较好、响应速度快、操作简单、成本较低等优点成为一种行之有效的方法，也是人们关注的焦点。

Eu 3+ @ 1 and Eu 3+ @ 2 in aqueous solution can achieve the quantitative detection of 2, 4, 6-trinitrobenzene (TNP), tetracycline (TC) and pesticides with high sensitivity and selectivity. In particular, when the volume of TNP increases to 50 μL, the luminescence quenching rate of Eu3+ @ 2 can reach 99.7% and the LOD for TNP can reach 78 nM.

2024年5月8日 · Highly sensitive fluorescent sensors for TNP have been developed for compounds having delocalized electrons and functional groups. The technique of fluorescence quenching serves as the foundation for the development of carbon dot-based (CD-based) fluorescent probes for nitroaromatic TNP [5].

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综上所述，该研究从ISDra2系统中 鉴定了一个新的具有dsDNA切割功能的核酸酶TnpB，其在原核和真核细胞中均能有效切割dsDNA，具有编辑人类基因组的巨大潜力。 在进化树上，虽然TnpB与微型 Cas12f 核酸酶的关系最为紧密，但作者认为两者之间依旧存在重大区别：（1）TnpB与Cas12f使用的guide RNA不同；（2）TnpB是单体，仅需要一个reRNA；而Cas12f 核酸酶是二聚体，需要结合一个拷贝的crRNA-tracrRNA duplex；（3）TnpB需要TAM序列，Cas12f需要PAM …

研究团队首先对ISfinder原核转座子数据库中IS605编码的TnpB蛋白进行了全面的分析和挖掘，从64个候选项中鉴定出了25种在大肠杆菌中活跃的系统，其中3种在人类细胞中具有基因编辑活性。 对于功能数据的进一步分析则揭示TnpB蛋白相关的reRNA骨架与IS200/IS605转座子的RE序列具有完全重叠的3’末端；而TAM序列则与转座子上游的插入位点序列相同。 该结果表明在TnpB系统中，与RNA介导的编辑器相关的三大要素（核酸酶、gRNA骨架和TAM序列）均可通过生物信息 …

2022年6月1日 · Due to rising threats of terrorism, pollution, timely and rapid detection of 2,4,6-trinitrophenol (TNP) and 2,4,6-trinitrotoluene (TNT) explosives has earned paramount significance. Herein, easily synthesized fluorenone sensor 3 was found selective towards the detection of TNP with a limit of detection (LOD) value of 0.5 nM.

2018年10月5日 · The polymers show highly selective and sensitive detection of 2,4,6-trinitrophenol (TNP) (picric acid). The selectivity for TNP is accomplished via combination of a strong inner filter effect (IFE), Förster resonance energy transfer (FRET) and photoinduced electron transfer (PET).