tRFs are 14-32 base long single-stranded RNA derived from mature or precursor tRNA and are distinct from the stress-induced tRNA fragments created by cleavage in the anti-codon loop. tRFs have been shown to be important for cell-cycle progression and for …

tRFtarget includes the computational predicted binding interactions between tRFs and target transcripts for multiple organisms based on the state-of-the-art prediction tools RNAhybrid and IntaRNA. tRFtarget can provide detailed information about the binding interactions as well as an illustration of the interaction sequences.

发现 Gly-tRF inhibitors（由锐博生物定制合成【RiboBio】） 治疗的小鼠血清ALT和AST水平显著降低，并且可显著降低酒精诱发的微泡和大泡性肝脂肪变性，但促炎细胞因子TNF-α和IL-6不受其影响。

2021年1月1日 · tRNA-derived fragments (tRFs) are a new category of regulatory noncoding RNAs with distinct biological functions in cancers and stress-induced diseases. Herein, we first summarize the classification and biogenesis of tRFs. tRFs are …

Time-Resolved Fluorescence (TRF) and TR-FRET (HTRF) are the powerful tools for drug discovery which enable the analysis of molecular interactions in biochemical processes like kinase assays, cellular signaling pathways, protein-protein interactions.

2019年12月5日 · Here, we present the X-ray structure of S. solfataricus Trf solved to a resolution of 1.65 Å. Trf is composed of an N-terminal rubredoxin-like domain containing a bound zinc ion and a C-terminal oligosaccharide/oligonucleotide binding fold domain. The Trf structure reveals putative mRNA binding sites in both domains.

2020年11月22日 · stow zsh 就是这么简单，先建立个总目录 ~/dotfiles，在此目录下，以软件名称为单位再建目录，将已有配置迁移到该目录下，然后运行 stow 即可。

2017年2月15日 · Here we present a study documenting repeatability data for a specific laboratory procedure for estimating telomere length using two common restriction enzymes, denaturing pulsed field gel electrophoresis, and a chemiluminescent detection system for three replicates of 16 individual red drum collected in South Carolina.

TRF具有多种生物学功能,包括作为应激反应中的信号分子和基因表达的调节因子。 此外,TRF还参与RNA加工、细胞增殖、翻译抑制、基因表型的遗传、细胞凋亡和免疫调节。

TRF Radio, Thief River Falls, Minnesota. 11,453 likes · 62 talking about this. Thief River Falls Radio -- KTRF 1230AM -- -- KKAQ 1460AM -- -- KKDQ...