Tristetraprolin regulates expression of VEGF and tumorigenesis
2010年4月15日 · Tristetraprolin (TTP) is an AU-rich element-binding protein that regulates mRNA stability. Here, we report that TTP suppress the growth of human colon cancer cells both in …
Tristetraprolin Inhibits Ras-dependent Tumor Vascularization …
In this complex phenomenon, tristetraprolin (TTP), an adenylate and uridylate-rich element-associated protein that binds to VEGF mRNA 3′-untranslated region, plays a key role by …
Tristetraprolin regulates the decay of the hypoxia-induced vascular ...
2016年10月26日 · The aim of the present study was to investigate the effects of tristetraprolin (TTP) on the vascular endothelial growth factor (VEGF) mRNA and protein expression levels …
Casein Kinase 2 Regulates the mRNA-destabilizing Activity of ...
2011年6月17日 · In this study, we demonstrate that CK2 increases the VEGF mRNA decaying activity of TTP in human colon cancer cells by protecting the TTP protein from phosphorylation …
Tristetraprolin regulates expression of VEGF and tumorigenesis in …
2009年8月20日 · Tristetraprolin (TTP) is an AU-rich element-binding protein that regulates mRNA stability. Here, we report that TTP suppress the growth of human colon cancer cells both in …
Tristetraprolin downregulates the expression of both VEGF …
TTP overexpression markedly decreased the expression of both COX-2 and VEGF in colon cancer cells. In addition, TTP inhibited the expression of luciferase linked to 3'UTR of COX-2 …
血管内皮生长因子 - 百度百科
血管内皮生长因子（vascular endothelial growth factor，VEGF），又称血管通透因子（vascular permeability factor，VPF）是一种高度特异性的促血管内皮细胞生长因子，具有促进血管通透 …
靶标解读丨血管生成关键因子—VEGF - 知乎
VEGF从多种细胞类型中释放，包括基质细胞，通过尖端和茎细胞的形成促进发芽，在胚胎发育和成人生活期间对组织维持和体内平衡至关重要（图4a左）。
Plasma Vascular Endothelial Growth Factor (VEGF) Levels Correlate …
2014年12月6日 · Plasma VEGF levels were increased in most patients with thrombocytopenia from ITP, sepsis and TTP, but not in patients who have thrombocytopenia from MDS, …
VEGF信号通路signaling pathway-武汉华美生物
VEGF通路起到保存现有血管的同时促进新血管生成的作用，VEGF与VEGFR-2结合后，会引起不同的级联信号通路。 武汉华美生物提供用于VEGF通路signaling pathway研究的蛋白、抗体、 …