味觉感受器，类型2，成员30，TAS2R30 是一个人类基因组中 TAS2R30 基因编码的蛋白质，是苦味味觉感受器的一员。 [1]

2024年12月25日 · TAS2R30 (Taste 2 Receptor Member 30) is a Protein Coding gene. Diseases associated with TAS2R30 include Submandibular Gland Disease. Among its related pathways are GPCR downstream signalling and Sensory perception of taste.

Taste receptor type 2 member 30 is a protein that in humans is encoded by the TAS2R30 gene. [5]

Gene ID: 259293, updated on 8-Feb-2025. Enables bitter taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Feb 2025]

2023年2月15日 · Herein we review the potential therapeutic role of TAS2Rs and bitter tasting compounds in cancer, specifically the expression of TAS2Rs in different types of cancer (e.g., breast, ovarian, and prostate) and the evidence showing the ability of bitter tasting compounds to overcome chemoresistance mechanisms in cancer. 2. Bitter taste receptors.

OriGene Order TAS2R30 cDNA clone/Protein/Antibody/RNAi Reactome Reactome Event:Sensory Perception Reactome Event:Signal Transduction Reactome Entity:P59541 Hide sidebar >>

2024年3月5日 · Enables bitter taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of …

FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).

TAS2R30 belongs to a family of intronless genes that encode highly related bitter taste receptors (TAS2Rs). TAS2Rs are G protein-coupled receptors, which are characterized by 7 transmembrane domains (summary by Fischer et al., 2005).

The gene view histogram is a graphical view of mutations across TAS2R30. These mutations are displayed at the amino acid level across the full length of the gene by default.