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Thyroid-stimulating antibody (TSAb) and TSH-binding inhibitor immunoglobulin (TBII) have been measured as TRAb to diagnose Graves' disease and to follow Graves' patients. We intended to evaluate the clinical value of TRAb (TSAb and TBII) assay in establishing the diagnosis of Graves' disease and in predicting its clinical course.

TRAb，即TSH受体抗体（TSH：促甲状腺激素）， 广义上可分为TSH受体刺激性抗体（TSAb）、TSH刺激阻断性抗体（TSBAb）和TSH受体结合抑制免疫球蛋白（TBII），在甲亢存在的情况下，则将TRAb定义为TBII。 它们与甲状腺细胞上的TSH受体结合，引起甲状腺增生及甲状腺激素分泌过多或过少，被认为是引起自身免疫性甲状腺疾病的重要因素之一。 TgAb，即甲状腺球蛋白抗体，是最早发现的甲状腺自身抗体， 其主要抗原是甲状腺滤泡胶质中的甲状腺球蛋白，具有 …

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2024年10月2日 · The thyrotropin receptor antibody (TRAb) test is a blood test that helps healthcare providers diagnose the autoimmune thyroid condition called Graves' Disease. The antibodies it tests for are present in between 90% and 100% of the people who have this disease. Other names for the TRAb test include:

The occurrence of thyrotropin binding inhibiting immunoglobulins (TBII) was studied in 144 patients with different types and stages of Graves' disease (GD) including 2 patients with primary hypothyroidism which changed into hyperthyroid GD.

In the present study, thyrotrophin binding inhibitor immunoglobulin (TBII) activites were measured by radioreceptor assay, according to the method of Shewring and Smith 1), in 30 patients with Graves’ disease, 13 patients with Hashimoto’s thyroiditis, 20 patients with lymphocytic thyroiditis with spontaneously resolving hyperthyroidism (LT ...

采用细胞培养生物学方法和放射受体分析法检测甲状腺疾病患者血清甲状腺刺激抗体（TSAb）和促甲状腺激素结合抑制免疫球蛋白（TBII）。 发现Graves病未治组TSAb和TBII活性与阳性率明显高于Graves病缓解组和桥本甲状腺炎（HT）组，后两组TSAb和TBII活性与阳性率高于甲状腺腺瘤组和正常对照组。 Graves病未治组、缓解组和HT组其TSAb和TBII的检出率分别为91.7％和79.2％、48.0％和44.0％及23.1％和61.5％。 甲状腺腺瘤组和对照组TSAb和TBII均为阴性， …

TSH receptor antibodies are antibodies that are often present in the serum of patients with Graves’ disease that are directed against the TSH receptor, often causing stimulation of this receptor with resulting hyperthyroidism. What is Graves’ disease? Graves' disease is an autoimmune disorder that can cause hyperthyroidism, or overactive thyroid.

TRAb (TSH Receptor Binding Antibody) - Measurement of TRAb is used to diagnose and manage Graves' disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes.