99m mTc-MDP是目前公认的较理想的骨显像剂。 通过化学吸附结合于骨骼的无机成分中的羟基磷灰石结晶(hydroxypatitecrystal)表面，此外骨内未成熟的胶原，也对 99m Tc-MDP有较高的亲和力。

Tc-99m methylene diphosphonate (Tc-99m MDP) 是目前最常使用來進行全身骨骼掃描的放射製劑。 靜脈注射Tc-99m MDP入血液後，Tc-99m MDP全進入骨骼與骨質成份中的礦物部份結合，尤其是沉積在 "非晶型的鈣磷化物" (cunorphous calcium phosphate) 中，少部份沉積在成熟的hydroxyapatite結晶中，因此在成骨活動 (osteogenic activity) 增強的病灶，就會有較強的Tc-99m MDP放射活性聚積現象。 由於Tc-99m MDP 是經由靜脈注射後隨血流運送到全身組織，所以 …

2007年3月29日 · Imaging with 99m Tc-methylene diphosphonate (99m Tc-MDP) is the initial method of choice to detect skeletal metastases in cancer patients (9). For SPECT of the bone, metastable technetium (99m Tc) is tagged onto a phosphonate compound such as MDP to generate 99m Tc-MDP, which selectively concentrates in the bone.

2022年1月6日 · Technetium 99m-methyl diphosphonate (99mTc MDP) is a radiotracer used in nuclear medicine especially for bone scintigraphy. Any disease process which results in extracellular fluid expansion will lead to accumulation of this tracer.

2025年2月1日 · Technetium Tc 99m medronate injection is used to help your doctor see an image of your bones to help diagnose bone problems. This medicine is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. None known at present. This class of compounds is...

MDP Multidose Kit for the Preparation of Technetium Tc99m Medronate Injection . DIAGNOSTIC - FOR INTRAVENOUS USE . DESCRIPTION . Each kit contains 10 multidose reaction vials, each containing...

2017年2月11日 · 99 Tc m -MDP全身骨扫描是最常用的核医学检查之一，临床上主要用于检出恶性病变骨转移及良性骨骼病变（如外伤、感染、代谢性骨病等）。 相比于其他针对骨骼系统的检查，骨扫描具有全身显像的优势，并且由于可以反映疾病早期的血流、代谢和功能改变，因此在诊断各种骨疾病上较X射线检查更为灵敏。 在临床工作中，除了骨骼常规显影和泌尿系统排泄通道偶然显影外，还经常可以观察到心肌、肝、脾、肌肉等软组织显像。 骨外软组织摄取的原因很 …

Technetium 99m-methyl diphosphonate (Tc-99m MDP) is an ideal bone scintigraphy agent due to its high bone-to-soft tissue uptake, rapid blood clearance, and good in-vivo stability. [1, 2, 3] Tc-99m MDP is chemisorbed on the bone tissue based on the osteoblastic activity of bony remodeling and blood flow to the tissue.

2024年8月8日 · Technetium Tc 99m medronate injection is used to help your doctor see an image of your bones to help diagnose bone problems. This medicine is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.