Transepithelial/transendothelial electrical resistance (TEER) is a widely accepted quantitative technique to measure the integrity of tight junction dynamics in cell culture models of endothelial and epithelial monolayers. TEER values are strong …

We demonstrate that these physical and technical parameters greatly influence the measurement of transendothelial electrical resistance/resistivity (TEER) across BBB culture models resulting in severalfold differences in TEER values of the same biological model, …

2016年1月1日 · Data suggest that 6 days of co-cultivation of HBMEC and NHA at a concentration of 1 × 10 5 cells insert −1 produces the most successful BBB model, as determined by the TEER value (160 ± 30 Ω cm 2). In addition, we validated the importance of NHA interactions with HBMEC in the formation of a tight BBB.

2025年1月23日 · 在BBB研究中，cellZscope能够实时监测BBB的跨膜阻抗值（TEER），TEER是衡量BBB功能紧密连接的重要参数。 通过TEER的变化，研究人员可以直观地了解BBB的通透性和屏障功能的强弱。

2021年6月11日 · The blood-brain barrier (BBB) represents the tightest endothelial barrier within the cardiovascular system characterized by very low ionic permeability. Our aim was to describe the setups, electrodes, and instruments to measure electrical resistance across brain microvessels and culture models of th …

2025年3月5日 · 在BBB研究中，cellZscope能够实时监测BBB的跨膜阻抗值（TEER），TEER是衡量BBB功能紧密连接的重要参数。 通过TEER的变化，研究人员可以直观地了解BBB的通透性和屏障功能的强弱。

One of the in vitro endothelial cell barrier models that have been commonly used for measuring TEER is the BBB model using human or rodent brain microvascular endothelial cells grown as a monolayer. In this protocol, we describe how TEER is measured in brain microvascular endothelial cell monolayers, to determine blood-brain barrier integrity ...

2015年1月13日 · Some of the barrier models that have been widely characterized using TEER include the blood–brain barrier (BBB), gastrointestinal (GI) tract, and pulmonary models. Variations in these values can arise due to factors such as temperature, medium formulation, and passage number of cells.

2023年2月13日 · An integrated indium tin oxide (ITO)–platinum (Pt), four-electrode TEER sensor enabled real-time TEER and optical monitoring of the BBB. TEER measurements were used to monitor the formation and dynamic changes of the barrier, while the highly transparent ITO electrodes enabled unrestricted optical access to the barrier model for high ...

Transepithelial/transendothelial electrical resistance (TEER) is a widely accepted quantitative technique to measure the integrity of tight junction dynamics in cell culture models of endothelial and epithelial monolayers. TEER values are strong ...