2016年11月10日 · We developed fully biodegradable/metabolizable nanosystem based on polymer surfactant-stabilized thermoresponsive solid lipid nanoparticles with non-covalently …

This study investigated a solid lipid nanoparticle (SLNP) system’s ability to bind and safely deliver siRNA in vitro. SLNPS were formulated using sphingomyelin and cholesterol, with Ginkgo …

2023年11月1日 · In this study, glioma cell membranes are used to encapsulate indocyanine green (ICG) loaded nanoparticles (SLNP/ICG), termed as SLNP/ICG@M for targeted photodynamic …

2025年1月10日 · In the present study, we constructed a tandem CRISPR/Cas13d system cleaving the conserved regions of the polymerase acidic (PA), nucleoprotein (NP), and matrix …

Visualize mRNA-loaded (left) and unloaded (right) lipid nanoparticle samples with cryo-TEM imaging. Cryotransmission electron microscopy (cryo-TEM) has long played a pivotal role in …

2025年2月8日 · Transmission electron microscopy (TEM) images further demonstrated homogeneous spherical nanoparticles in both sLNPs-OVA and sLNPs-OVA/Cel formulations …

Tumor‐associated macrophages (TAMs)—representative immune‐suppressive cells in the tumor microenvironment (TME)—are known to promote tumor progression and metastasis,...

2021年10月4日 · The physicochemical characterization of BSE loaded solid lipid nanoparticles (BSE-SLNp) has been analyzed using Zetasizer, FT-IR, and TEM. The BSE-SLNp showed an …

SLNPs were successfully prepared with smaller particle size of 67.63 ± 5.02 nm, higher DL% of 5.58 ± 0.41% and PDI of 0.159 ± 0.018 ( Fig. S1 and Table S1). The particle size and TEM …

2020年10月27日 · In this study, the “cell-chemotherapy” strategy was presented to enhance antitumor efficacy. M1-type macrophages, which are therapeutic immune cells with both of …