T helper 17 cell - Wikipedia
IL-17 family cytokines (IL-17A and IL-17F) target innate immune cells and epithelial cells, among others, to produce G-CSF and IL-8 (CXCL8), which leads to neutrophil production and …
Th17 Cytokines and Barrier Functions - PMC
Most Th17 cells were found to reside in the barrier tissues, including respiratory and intestinal tracts as well as skin. Cytokines produced by these Th17 and non-Th17 cells play critical roles …
Th17 cells in human disease - PMC - PubMed Central (PMC)
IL-17 is a highly inflammatory cytokine with robust effects on stromal cells in many tissues. Recent data in humans and mice suggest that Th17 cells play an important role in the pathogenesis of …
T Helper 17 Cells Overview | Thermo Fisher Scientific - US
Th17 cells can be differentiated in vitro from CD4 + T cells using recombinant cytokines to induce polarization and functional antibodies to prevent signaling from cytokines that promote …
The Biological Functions of T Helper 17 Cell Effector Cytokines in ...
The effector cytokines of Th17 cells, such as IL-17, IL-21, and IL-22, are potential future therapeutic targets. A challenge is to figure out the balance between their beneficial and …
Defining the TH17 cell lineage | Nature Reviews Immunology
2021年9月27日 · CD4 + T helper (T H) cells produce cytokines to regulate immune responses; T H 1 cells and T H 2 cells, which were discovered in the 1980s, have important roles in …
Th17 cytokines and their emerging roles in inflammation and ...
The cytokines made by Th17 cells represent three distinct gene families, highlighting the unique biology of these cells. Accumulating data support a role for Th17 cells and these cytokines in …
The Role of TH17-Associated Cytokines in Health and Disease
2014年4月29日 · Morishima et al. highlight the role of T H 17-associated cytokines in asthma, especially in steroid-resistant disease. Further interesting findings from the Hizawa laboratory …
Th17 Cell - an overview | ScienceDirect Topics
Th17 cells are a subset of CD4+ effector T cells characterized by expression of the IL-17-family cytokines, IL-17A and IL-17F. Since their discovery nearly a decade ago, Th17 cells have …
The crucial roles of Th17-related cytokines/signal pathways in
2017年11月27日 · Here, we review Th17-related cytokines/Th17-like cells, networks/signals and their roles in immune responses or immunity against Mycobacterium tuberculosis (Mtb) infection.