The ribosomal DNA (abbreviated rDNA) consists of a group of ribosomal RNA encoding genes and related regulatory elements, and is widespread in similar configuration in all domains of life.

Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together genetic material from multiple sources, creating sequences that would not otherwise be found in the genome.

Genes encoding ribosomal RNA (rDNA) are essential for cell survival and are particularly sensitive to factors leading to genomic instability. Their repetitive character makes them prone to inappropriate recombinational events arising from collision of transcriptional and replication machineries, resulting in unstable rDNA copy numbers.

Ribosomal DNA (rDNA) refers to the genes responsible for encoding ribosomal RNA (rRNA). You might find these chapters and articles relevant to this topic. The genes that encode the ribosomal RNA (rRNA). The nontranscribed segment between neighboring transcription units.

The ribosomal RNA gene (rDNA) repeats form a historically well-researched region in the chromosome. Their highly repetitive structure can be identified easily which has enabled studies on DNA replication, recombination, and transcription.

2023年2月2日 · Recent studies have elucidated mechanisms underlying the integrity of ribosomal DNA and regulation of its transcription, including epigenetic mechanisms and a unique recombination and copy-number...

2022年4月1日 · rDNA is a major, evolutionarily conserved biosynthetic hub responsible for the production of rRNAs (Box 1). Transcription of rDNA gives rise to precursor rRNA species that undergo multiple processing steps and associate with ribosomal proteins to assemble preribosomal subunits (reviewed in [1]).

Eukaryotic cells have evolved a ribosomal DNA (rDNA) transcription machinery that incorporates RNA polymerase I (pol I), an enzyme dedicated to this pursuit. rDNA transcription is confined to the nucleolus, which is the site of ribosome biogenesis.

2021年5月19日 · Recombinant DNA technology refers to the joining together of DNA molecules from two different species that are inserted into a host organism to produce new genetic combinations that are of value to science, medicine, agriculture, and industry.

2022年3月8日 · One such element is ribosomal DNA (rDNA), the highly conserved genomic region that encodes rRNAs. Genomic structure and content of the rDNA are variable in both prokarya and eukarya, posing interesting questions about the biology of rDNA.