T helper cell effector fates — who, how and where?
2006年6月1日 · ThFH cells, which were first identified in humans, represent T cells found in germinal centers that possess a cytokine profile distinct from Th1 and Th2 cells. ThFH cells …
T滤泡辅助(Tfh)细胞相关调控的细胞因子 - 知乎 - 知乎专栏
2024年1月23日 · Tfh细胞（Follicular helper T cell）是参与体液免疫的辅助性T细胞亚群，直接来源于初始T细胞，存在于扁桃体、淋巴结等淋巴组织中。 Tfh细胞分泌细胞因子刺激B细胞增殖 …
Tfh细胞及其相关的细胞因子 - 知乎 - 知乎专栏
Tfh细胞（Follicular helper T cell）是参与体液免疫的辅助性T细胞亚群，直接来源于初始T细胞，存在于扁桃体、淋巴结等淋巴组织中。 Tfh细胞分泌细胞因子刺激B细胞增殖以及免疫球蛋白的 …
The good, the bad and the ugly — TFH cells in human health and …
2013年5月17日 · Naive CD4 + T cells have the potential to differentiate into specialized effector cell populations that have distinct functions during infection; T follicular helper (T FH) cells are …
T follicular helper cell heterogeneity: Time, space, and function
We herein review the heterogeneity of Tfh cells marked by the dynamic phenotypic changes accompanying their developmental program. Focusing on the various locations where Tfh and …
T follicular helper (TFH) cells in normal and dysregulated immune ...
Only recently has a better understanding of the cellular and molecular mechanisms for T cell help emerged. A subset of T cells, termed T follicular helper cells (T (FH) cells), provides a helper …
T helper 2 and T follicular helper cells: Regulation and Function of ...
In addition to the Th2 cells, recent studies have identified T follicular helper (Tfh) cells as an alternative source of IL-4 to regulate type 2 humoral immune responses, indicating that Th2 …
人辅助性T细胞（Th）亚群分化方案及细胞因子的选择
根据活化的 CD4+Th所分泌的细胞因子谱，分为 Th1、Th2、Th17、调节性T细胞 (Treg)、Th9、Th22、Tfh细胞。 每个亚群都由一组特定的细胞因子和转录因子活化，并以他们分泌的细胞因 …
人辅助性T细胞（Th）亚群分化方案及细胞因子的选择 - 企业动态
2024年8月27日 · 淋巴结T细胞区的并指状DC (interdigitating DC)表面 pMHC 与初始 CD4 + T细胞TCR高亲和力结合，可启动 CD4 + T 细胞分化为Tfh 细胞。 该类细胞可对免疫应答进行精细 …
T follicular helper cell heterogeneity: Time, space, and function
We herein review the heterogeneity of Tfh cells marked by the dynamic phenotypic changes accompanying their developmental program. Focusing on the various locations where Tfh and …