Tiagabine (trade name Gabitril) is an anticonvulsant medication produced by Cephalon that is used in the treatment of epilepsy. The drug is also used off-label in the treatment of anxiety disorders and panic disorder .

噻(sāi)加宾，又名替加宾，（英文名：Tiagabine），一种有机化合物。 化学式是C₂₀H₂₅NO₂S₂，分子量为375.55。 白色至类白色结晶性粉末，无臭。

2025年2月10日 · Tiagabine is an anti-epileptic medication, also called an anticonvulsant. Tiagabine is used in combination with other medications to treat partial seizures in adults and children who are at least 12 years old. Tiagabine may also be used for purposes not listed in this medication guide.

2005年6月13日 · Tiagabine is an antiepileptic used to treat partial seizures. Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants.

Tiagabine is used in combination with other medications to treat partial seizures (a type of epilepsy). Tiagabine is in a class of medications called anticonvulsants. It is not known exactly how tiagabine works, but it increases the amount of …

Tiagabine is used to help control some types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it. Tiagabine is available only with your doctor's prescription.

Tiagabine (TGB) is a recently approved antiepileptic drug (AED) that inhibits y-aminobutyric acid (GABA) reuptake into neurons and glia, a mechanism of action that is specific and unique among the AEDs. TGB is potent and has linear and predictable pharmacokinetics.

Understanding the molecular basis of the B 0 AT2 inhibition by loratadine led to the discovery of a new inhibitor that is tiagabine, an anticonvulsant drug prescribed off-label in the treatment of anxiety and possessing antidepressant features. The results showed that tiagabine appears to have a higher affinity to the transporter than ...

2024年1月7日 · Tiagabine Hydrochloride tablets are an antiepilepsy drug available as 2 mg, 4 mg, 12 mg, and 16 mg tablets for oral administration. Its chemical name is (-)- (R)-1- [4,4-Bis (3-methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride, its molecular formula is C 20 H 25 NO 2 S 2 HCl, and its molecular weight is 412.0.

2012年11月27日 · Tiagabine is a γ-aminobutyric acid (GABA) uptake inhibitor which is structurally related to nipecotic acid but has an improved ability to cross the blood-brain barrier. Clinical trials have shown that tiagabine is effective as add-on therapy in the management of patients with refractory partial epilepsy.