TIM3 expression on TILs is associated with poor response to ... - PubMed
2021年4月6日 · These findings demonstrate that CTLA-4, PD-1, PDL-1, and TIM-3 were highly expressed in TNBC. Based on these high expression patterns, further studies directed towards …
The immune checkpoint TIGIT/CD155 promotes the exhaustion of …
2024年1月12日 · We evaluated CD155 and TIGIT expression in TNBC tissues using both immunohistochemistry (IHC) and gene expression profiling. Our experiments, both in vivo and …
TIM-3 as a promising target for cancer immunotherapy in a
2023年8月11日 · TIM-3 is one of the key immune checkpoint receptors that interact with GAL-9, PtdSer, HMGB1 and CEACAM1. Initially identified on the surface of T helper 1 (Th1) …
TILs上的TIM3表达与局部晚期三阴性乳腺癌患者对新辅助化疗的不 …
因此，我们调查了新辅助化疗（NAC）后局部晚期三阴性乳腺癌（TNBC）患者TILs上各种ICR表达。 使用针对PDL-1，PD-1，TIM-3，LAG-3和CTLA-4的单克隆抗体，对外科标本（n = 61） …
Therefore, we investigated various ICR expressions on TILs in patients with locally advanced triple-negative breast cancer (TNBC) after neoadjuvant chemotherapy (NAC). Methods: …
Quiescent cancer cells: Therapeutic targets to overcome …
2022年6月10日 · Tumor cells constitutively expressing HIF1α were associated with reduced content of both MHC class II-expressing dendritic cells and CD8+ TIM3− T cells. Moreover, …
(PDF) TIM3 expression on TILs is associated with poor response to ...
2021年4月6日 · Therefore, we investigated various ICR expressions on TILs in patients with locally advanced triple-negative breast cancer (TNBC) after neoadjuvant chemotherapy …
Clinical Significance of Expression of Immunoadjuvant Molecules (LAG …
2022年1月2日 · Conclusion: Our findings suggest that LAG-3 may become a biomarker in highly malignant breast cancers such as TNBC and HER2BC that can predict the therapeutic efficacy …
Immunotherapy Combinations and Dual Checkpoint Blockade
2024年11月7日 · In a study of 95 specimens of invasive breast cancer (34% luminal A, 33% luminal B, 20% HER2, and 13% TNBC), TIM3 expression (defined as >1% TIM3+ TILs by a …
TIM3 expression on TILs is associated with poor response to …
2021年4月6日 · These findings demonstrate that CTLA-4, PD-1, PDL-1, and TIM-3 were highly expressed in TNBC. Based on these high expression patterns, further studies directed towards …