Risk prediction model for taxane-induced peripheral neuropathy (TIPN …
2024年5月29日 · Background: TIPN can impact the ability to complete cancer treatment as well as patient quality of life and functional status. To create a risk prediction model for TIPN, a …
Quantitation of Plasma Proteins to Predict Taxane-Induced
2025年1月31日 · Purpose: Taxane-induced peripheral neuropathy (TIPN) is a dose-limiting toxicity of paclitaxel in patients with cancer. TIPN prediction is challenging although patients …
Genome-Wide Association Studies for Taxane-Induced Peripheral …
2015年11月15日 · Purpose: Taxane-induced peripheral neuropathy (TIPN) is an important survivorship issue for many cancer patients. Currently, there are no clinically implemented …
Taxane-induced neuropathy: How serious is this problem for
Taxane-induced peripheral neuropathy (TIPN) is a common toxicity and confers significant morbidity with no validated therapies. Literature detailing TIPN is inconsistent in reporting its …
A Multimodal Approach to Discover Biomarkers for Taxane …
Taxane-induced peripheral neuropathy (TIPN) occurs in up to 70% of patients, impacting quality of life both during and after treatment. TIPN typically manifests as tingling and numbness in …
PLOS GENETICS：揭示SBF2对紫杉烷诱导的周围神经病变的影响
虽然紫杉烷有助于改善整体癌症的长期生存率，但它们的毒性，诱导的周围神经病变（tipn），是患者最重要的生存问题之一。 TIPN的症状因人而异，可能是严…
【科研背后】提高疗效与改善生活质量并重——GM1显著降低紫杉 …
2019年8月29日 · 紫杉类药物引起的周围神经毒性（tipn） 然而，紫杉类药物引起的周围神经毒性（Taxane-induced peripheral neuropathy，TIPN）是剂量限制性毒性，主要表现为肢端麻木、 …
多发性骨髓瘤周围神经病变诊疗中国专家共识（2015年）
2017年2月6日 · tipn的发生可能与沙利度胺抗血管新生作用相关，致使神经纤维缺血、tnfα表达下调、nf–κb通路阻断，进而诱发神经纤维的损伤、促发神经细胞死亡等[]。
Taxane-Induced Peripheral Neurotoxicity - PMC
Taxane-induced peripheral neuropathy (TIPN) is problematic for several reasons. First, it is a growing issue due to improved long-term cancer survival. More cancer patients live longer or …
Quantitation of Plasma Proteins to Predict Taxane-Induced …
2025年1月31日 · Taxane-induced peripheral neuropathy (TIPN) is a dose-limiting toxicity of paclitaxel in patients with cancer. TIPN prediction is challenging although patients with higher …