2024年8月1日 · Total metabolic tumor volume (TMTV) is prognostic in lymphoma. However, cutoff values for risk stratification vary markedly, according to the tumor delineation method used. We aimed to create a standardized TMTV benchmark dataset allowing TMTV to be tested and applied as a reproducible biomarker.

2014年2月26日 · In patients, TMTV was measured on PET at staging by two methods: volumes of individual lesions were measured using a fixed 41 % SUVmax threshold (TMTV 41) and a variable visually adjusted SUVmax threshold (TMTV var).

2024年12月16日 · We aimed to explore the predictive value of total metabolic tumor volume (TMTV) and beta-2-microglobulin (B2M) levels in patients with follicular lymphoma (FL) with a high tumor burden receiving standard first-line immunochemotherapy.

One such parameter is total metabolic tumor volume (TMTV), which is the total 3-dimensional volume of all FDG-avid lesions on PET-CT. 25, 34 TMTV has been found in 1 study to be an independent predictor of outcome in grade 1 to 3 high tumor burden FL, 35 but not predictive of outcome in another study of favorable grade 1 to 2 FL. 36 A second ...

2023年9月18日 · The optimal cutoff values for TMTV were determined to be 36.42 and 37.51 cm 3 for predicting 2-year PFS and OS, respectively. Patients with high TMTV exhibited significantly inferior 2-year PFS (Fig. 3B, P < 0.001) and OS (Fig. 4B, P < 0.001), with rates of 22.4% and 38.1%, respectively, compared to those with low TMTV, who had rates of 85.8% ...

2021年8月11日 · TMTV is a unique and easy tool that could replace the surrogate of tumor burden included in the prognostic indexes used in lymphoma and help tailor therapy. Other parameters extracted from the baseline PET may give an information on the dissemination of this total tumor volume such as the maximum distance between the lesions.

FDG-PET-based TMTV measurement brings useful, independent, and correlative information to the clinical drug evaluation process. Clario can customize the segmentation threshold settings …

2020年7月23日 · 通过PRT-CT扫描并应用41%的最大标准化摄取值阈值法计算出的总肿瘤代谢体积（TMTV）可以评估肿瘤负荷，并且已经证实与霍奇金淋巴瘤，滤泡性淋巴瘤和未治疗的DLBCL的预后相关。 本研究通过对REMARC临床试验（NCT01122472）来评估基线TMTV是否对R-CHOP治疗有效的老年患者是否具有预后价值。 方法. 在REMARC临床试验中，经过6或8个周期的标准R-CHOP治疗后获得CR或PR的650名60-80岁老年DLBCL患者被随机分配1：1分别给予 …

2016年10月9日 · 法国研究者Michel Meignan等报告，在滤泡 淋巴瘤 (FL)患者中，基线肿瘤代谢总体积 (TMTV)是一个较好的独立预后因素。 同滤泡性 淋巴瘤 国际预后指数2 (FLIPI2)评分结合，能作为疾病早期进展的识别标志。

2023年4月6日 · Te mostramos en este programa un resumen de actividades que tuvieron lugar en Posadas y también en la provincia. Misiones tiene mucho por descubrir y lo hacemos juntos. Anticiclón del Pacífico Sur: ¿Qué es y cómo afectará a …