A novel D–π–A–π–D-type organic small molecule (OSM) named (TPACN)2Qx was designed and synthesized for solution-processible organic solar cells (OSCs), which contained 2,3-diphenyl-substituted...

2025年2月20日 · The resultant polyoxalate (designated TPACN@PEG) can self-assemble into water dispersible nanoparticles with suitable size (about 130 nm), endowing its passive tumor targeting potential via enhanced permeability retention effect. TPACN@PEG can be degraded into small molecules by reaction with H 2 O 2. Owing to the typical donor-acceptor ...

2023年8月10日 · With its good water solubility and small size, TPACN-D-Ala could penetrate and diffuse into bacterial biofilms relatively easily. Consequently, TPACN-D-Ala could accumulate rapidly on the methicillin-resistant Staphylococcus aureus (MRSA) biofilms (Figure 4 B). Furthermore, most of the bacteria residing within the biofilms could be ...

In this study, we developed a bacterial metabolic probe TPACN- D -Ala, which combines an AIE PS with D -alanine (D -Ala), with activatable fluorescence and strong 1 O 2 generation capability to realize precise in vivo tracking and efficient eradiation of bacteria in one step.

Capitalizing on the one-step direct metabolic labeling strategy, in our subsequent work, we further engineered an AIEgen-based synthetic theranostic platform to overcome drug-resistant bacterial infections . 51 Here, a bacterial metabolic probe TPACN-D-Ala with activatable fluorescence and strong photosensitization was generated by combining an ...

2017年5月3日 · A novel D–π–A–π–D-type organic small molecule (OSM) named (TPACN) 2 Qx was designed and synthesized for solution-processible organic solar cells (OSCs), which contained 2,3-diphenyl-substituted quinoxaline (Qx) as the central acceptor (A) unit, triphenylamine (TPA) as terminal electron-donor (D) moieties, and acrylonitrile as the π ...

2021年4月13日 · 本文中，研究团队设计合成了一种具有高固态亮度的有机分子TPACN，通过Stober方法在纳米颗粒表面包裹上一层二氧化硅壳层，该纳米颗粒表面光滑、尺寸均匀、亮度高，稳定性高，Stokes位移大，同时，通过飞秒瞬态吸收证明了纳米颗粒高的受激辐射的存在，因此该探针非常有利于STED超分辨成像 （图一）。 图一. 随后，研究者考察了TPACN纳米颗粒的STED成像效果。 研究者发现探针不仅可以被拖尾处的775纳米STED光可以进行损耗，同时 …

一种新的命名为d-π-A-π-d型有机小分子（OSM）（TPACN）2 QX被设计和用于溶液加工的有机太阳能电池（OSC）中合成，其中载-2,3-二苯基喹喔啉基取代（Qx）作为中心受体（A）单元，三苯胺（TPA）作为末端电子给体（D）部分，丙烯腈作为π键链段。 （TPACN）2 Qx具有有效的吸电子性能和相对稳定的Qx喹诺酮几何形状，其窄带隙为1.88 eV，在300-700 nm处具有强而宽的吸收。 结果，基于（TPACN）2 Qx：PC 61获得了6.25％的出色功率转换效率（PCE）。 在溶液 …

在这项研究中，我们报告了装载新型有机荧光染料 (TPACN) 的纳米造影剂 (Tnano) 的制造及其细胞成像性能的评估。 这种纳米造影剂不仅保留了 TPACN 的光学特性，包括 67% 的优异荧光量子产率 (QY) 和 165 nm 的大斯托克斯位移，而且与游离 TPACN 相比，还表现出显着的胶体和荧光稳定性，以及卓越的生物相容性和增强的细胞成像能力。 鉴于这些有利的特性，我们的载有 TPACN 的纳米造影剂可能在未来应用于生物成像和生物医学用途。 更新日期：2019-12-01. 摘 …

2019年12月15日 · In present study, we designed and synthesized a novel organic dye,2-((4-(diphenylamino)phenyl)(phenyl)methylene)malononitrile (TPACN), and encapsulated it with a biocompatible polymer, Pluronic F127, to form a nanocontrast agent (T nano). And the size, morphology, and optical properties of T nano were carefully characterized. We further tested ...