A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and …
One such tRF, a 5’ fragment of tRNA-Glu-CTC (tRF5-Glu), is processed from the mature tRNA-Glu and is shown in this study to be expressed in ovarian cancer cells. We confirmed that …
Radiotherapy plus a self-gelation powder encapsulating tRF5 …
2025年2月10日 · To target tRF5-GlyGCC in HCC cells, we synthesized the tRF5-GlyGCC inhibitor (tRF5-Gi), a kind of single stranded nucleotide. However, the naked single stranded nucleotide …
The nuclear poly(A) polymerase and Exosome cofactor Trf5 is …
Several TRAMP components (Air1, Air2, Mtr4, Trf4, and Trf5) and two catalytic Exosome subunits (Rrp44 and Rrp6) were tested (Fig. 7A). Both Trf4 and Trf5 were significantly coenriched …
The Importance of AGO 1 and 4 in Post-Transcriptional Gene ... - PubMed
2020年11月20日 · We have recently shown that a tRNA-derived RNA fragment (tRF) from the 5'-end of mature tRNA encoding GluCTC (tRF5-GluCTC), a recently discovered non-coding …
An emerging role of the 5′ termini of mature tRNAs in human …
2022年2月1日 · Combining 5'-tiRNAs and tRF-5 into a single category: 5′-tRFs, we summarized that 5′-tRFs are equipped with unique enrichment and functional advantages. 5′-tRFs …
Regulatory roles of tRNA-derived RNA fragments in human pathophysiology
2021年12月3日 · Advancement in deep-sequencing technologies have revealed the presence of abundant expression of functional tRNA-derived RNA fragments (tRFs). They are either …
Identification and Functional Characterization of tRNA-derived …
2013年2月1日 · In this study, we have analyzed the global expression profile of sncRNAs in RSV-infected airway epithelial cells by Illumina ultra-high–throughput sequencing in order to identify …
tRFs and tRNA Halves: Novel Cellular Defenders in Multiple …
Viral infection may induce tRF production in host cells. tRF5-Glu-CTC represses target mRNA expression in a non-canonical miRNA manner and promotes RSV infection . Furthermore, …
Unique tRNA Fragment Upregulation with SARS-CoV-2 but Not …
2023年12月28日 · We found tRF5 expressions to be distinctively upregulated in CoV2-infected cell lines and nervous system-related KEGG pathways to be enriched among downregulated …
The Importance of AGO 1 and 4 in Post-Transcriptional Gene
2020年11月20日 · We have recently shown that a tRNA-derived RNA fragment (tRF) from the 5′-end of mature tRNA encoding GluCTC (tRF5-GluCTC), a recently discovered non-coding …