2023年7月1日 · A ROS-responsive hydrogel was prepared via cross-linking PVA with N 1-(4-boronobenzyl)-N 3-(4-boronophenyl)-N 1,N 1,N 3,N 3-tetramethylpropane-1,3-diaminium (TSPBA). The 1 H NMR spectrum of TSPBA well matched its desirable chemical structure (Fig. S1), which confirmed the successful

2023年6月10日 · Pure TSPBA was obtained after volatilizing THF under vacuum overnight 27,47. The structure was characterized by 1 H NMR (BRUKER AVIII500M).

2013年5月9日 · ChemicalBook Provide Tetrabutylammonium fluoride(429-41-4) 1H NMR,IR2,MS,IR3,IR,1H NMR,Raman,ESR,13C NMR,Spectrum. Welcome to chemicalbook! +1 (818) 612-2111. 18162-48-6 872-50-4 Methylene Chloride naphthalene THF Titanium Dioxide. Structure Search Inquriy.

2023年5月1日 · A novel in situ formed pH/ROS dual-responsive, injectable, and self-healing TSPBA-PVA niche-like hydrogel encapsulated with TiOx@CaO 2 and aPD-L1 for SDT/CDT potentiated anti-tumor immunotherapy, exhibiting great potential for treating easily metastasized triple-negative breast cancer.

The PVA-TSPBA hydrogel developed herein, capable of encapsulating VHH, demonstrates excellent biocompatibility and responsiveness to reactive oxygen species (ROS). This positions it as a promising candidate for drug delivery in MI therapy.

TSPBA，全称为N1- (4-溴苄基)-N3- (4-溴苯基)-N1,N1,N3,N3-四甲基丙烷-1,3-二胺，作为一种对活性氧（ROS）具有响应性的交联剂，在生物医学及材料科学领域内展现出广泛的应用潜力与重要价值。 其ROS响应特性根植于其分子结构中独特的官能团，这些官能团能与ROS发生特异性反应，诱发TSPBA化学结构的转变，进而激活一系列连锁反应。 这种独特的响应机制使得TSPBA能在ROS存在的条件下执行特定的化学行为，诸如交联、降解或药物释放等。 鉴于TSPBA的研究 …

Tspba | C21H34B2Br2N2O4 | CID 138113109 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

有文献表明合成活性氧响应性交联剂N1- (4-溴苄基)-N3- (4-溴苯基)-N1,N1,N3,N3-四甲基丙烷-1,3-二胺 (TSPBA),混合相应成分制成 聚乙烯醇-TSPBA (PVA-TSPBA)微针，可顺利刺穿小鼠皮肤并能通过缓慢响应创面中的活性氧从而溶解释放抗菌物质，抑制创面细菌定植，促进 糖尿病小鼠 细菌定植全层皮肤缺损创面修复。 另外有研究表明具有活性氧响应性且力学性能良好的抗菌微针可顺利刺穿皮肤并缓慢响应创面微环境中的活性氧从而溶解释放抗菌药物以促进创面修复。 这种微 …

2025年3月14日 · tspba是一种含有甲基丙烯酰氧基的苯酚类化合物，具有可聚合性。 当与PVA一起共聚合时，TSPBA可以在PVA水凝胶中引入交联结构，从而增加水凝胶的稳定性和力学强度。

2024年7月27日 · The ROS-responsive TSPBA linker was synthesized and then characterized by Nuclear magnetic resonance spectroscopy (1 H-NMR) (Fig. S2) [36, 37]. We investigated the impact of varying PVA and TSPBA concentrations on gel flexibility (Fig. S3a). A concentration of 3% TSPBA effectively cross-linked with 9% PVA, resulting in a flexible gel.