Tubulitis in the kidney is defined as the presence of inflammatory cells in the tubular wall (OOi et al. 1975). It is the hallmark of tubulointerstitial nephritis (OLsen etal. 1986) and one of the important lesions in acute renal allograft rejection (SOlez et al....

Tubulopathy is a disease affecting the renal tubules of the nephron. [1] Tubulopathic processes may be inflammatory or noninflammatory, though inflammatory processes are often referred to specifically as tubulitis. [2][3]

Tubulointerstitial nephritis (TIN) is a frequent cause of acute kidney injury (AKI) that can lead to chronic kidney disease (CKD). TIN is associated with an immune-mediated infiltration of the kidney interstitium by inflammatory cells, which may progress to fibrosis.

肾小管间质性肾炎是肾小管及其周围组织（间质组织）的炎症。 病因包括损害肾脏的疾病、药物及毒素。 患者有尿痛、腰或侧腹疼痛、发热或皮疹。 血和尿化验可以发现肾损害。 停止暴露于有害药物或毒素并治疗基础疾病可以改善肾功能。 （也请参阅肾脏滤过疾病概述。 肾小管间质性肾炎常导致肾衰竭（失去大部分肾功能）。 可由多种疾病、药物、毒素或放射线损伤肾脏而引起。 肾小管损伤导致血液中电解质（例如钠和钾）的量变化或肾脏浓缩尿液的能力问题，导致尿液过 …

Tubulitis is the principal lesion used for the diagnosis of acute rejection (AR) in the Banff schema for renal allograft pathology. It is considered to be reliable for assessing AR early after transplantation. However, its significance in biopsies with …

1995年12月1日 · Introduction The term tubulitis denotes the presence of inflamma­tory cells in the renal tubular wall. Tubulitis comprises an important part of the histopathology in acute pye­lonephritis25, acute allergic interstitial nephritis23 and acute renal allograft rejection22,44.

Acute interstitial nephritis (AIN) describes a lesion with interstitial edema with a mononuclear cell infiltrate invading the interstitium and tubules, composed mostly of T lymphocytes. There are scattered plasma cells and macrophages, occasionally with non-necrotizing granulomas, and variable presence of eosinophils.

Tubulitis in the kidney is defined as the presence of inflammatory cells in the tubular wall (001 et al. 1975). It is the hallmark of tubulointerstitial nephritis (OLSEN et al. 1986) and one of the important lesions in acute renal allograft rejection (SOLEZ et al. 1993).

This prospective observational cohort study compared the impact of subclinical tubulitis with or without interstitial inflammation to interstitial inflammation alone and to no inflammation in early post kidney transplant biopsies.

Tubulitis without interstitial inflammation (Banff i0), termed "isolated tubulitis" (ISO-T), has been controversially included within the Banff "borderline" category of acute T cell mediated rejection (TCMR). This single-center, retrospective, observational study of …