2024年12月25日 · TYROBP (Transmembrane Immune Signaling Adaptor TYROBP) is a Protein Coding gene. Diseases associated with TYROBP include Polycystic Lipomembranous …

TYRO protein tyrosine kinase -binding protein is an adapter protein that in humans is encoded by the TYROBP gene. [5][6] This gene encodes a transmembrane signaling polypeptide which …

该基因内的突变与多囊性脂膜性骨发育不良伴硬化性白质脑病 (PLOSL) ，也称为 Nasu-Hakola 病有关。 其推定的受体，即髓样细胞 2 (TREM2) 上表达的触发受体，也会引起 PLOSL。 已经 …

TREM1（Triggering receptor expressed on myeloid cells-1）是一种在中性粒细胞、单核细胞、巨噬细胞表面表达的髓系细胞表面受体，在多种肿瘤微环境中均表达，协同经典的 模式识别受 …

2024年8月30日 · Immune infiltration correlation analysis shows that the top-ranked signature gene, Tyrobp, is negatively correlated with M2 macrophages and plasma cells, and Western …

TYROBP（也称为 DAP12 或 KARAP）是一种跨膜衔接蛋白，最初被描述为自然杀伤 (NK) 细胞的受体激活亚基成分。 TYROBP 在多种细胞类型中表达，包括外周血单核细胞、巨噬细胞、树 …

The TYROBP gene provides instructions for making the TYRO protein tyrosine kinase binding (TYROBP) protein. This protein is found in a variety of cells that are produced in bone marrow …

TYROBP is a potential prognostic biomarker of clear cell renal cell carcinoma. Non-pathological roles of microglial TREM2/DAP12: TREM2/DAP12 regulates the physiological functions of …

2025年2月19日 · Clinical resource with information about TYROBP, Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1, and available tests. There are links to …

DAP12 (DNAX-activating protein 12)/TYROBP, a molecule localized to microglia, is a direct partner/adapter for TREM2, CD33, and CR3. We and others have previously shown that …