
Discovery of safety biomarkers for realgar in rat urine using UFLC …
2013年3月13日 · Using a combined ultrafast liquid chromatography (UFLC) coupled with ion trap time-of-flight mass spectrometry (IT-TOF/MS) and 1 H NMR spectroscopy based metabolomics approach, we were able to delineate significantly altered metabolites in the urine samples of realgar-treated rats.
Identification, characterization and in silico ADMET prediction of ...
2017年5月10日 · HPLC methods were adapted to determine the molecular identity of the isolated DPs, using ultra-fast liquid chromatography (UFLC) (Nexera, Shimadzu, Japan). The UFLC system was equipped with a quadrupole time-of-flight detector mass spectrometer (QTOF) Compact™ and controlled using Compass Data Analysis software, version 4.2 …
Discovery of safety biomarkers for realgar in rat urine using UFLC …
Using a combined ultrafast liquid chromatography (UFLC) coupled with ion trap time-of-flight mass spectrometry (IT-TOF/MS) and (1)H NMR spectroscopy based metabolomics approach, we were able to delineate significantly altered metabolites in the urine samples of realgar-treated rats.
Center for Nuclear Magnetic Resonance Spectroscopy – University …
2025年1月22日 · More than 200 users, students and faculty, mainly from the Chemistry Department but also from around the campus, and researchers from industry use the instruments in our facility to check the outcome of reactions or characterize compounds. Many synthetic chemists use our facility on a daily basis.
UFLC/MS-IT-TOF guided isolation of anti-HBV active chlorogenic …
2014年10月28日 · LC/MS and bioassay-guided fractionation on the active extract of Artemisia capillaris led to the isolation of nine chlorogenic acid analogues. Structures of the isolates were elucidated by MS/MS and NMR techniques.
Development and UFLC-MS/MS Characterization of a Product …
2016年5月5日 · For this project, we were able to leverage our group’s access to authentic lignan standards (previously isolated and identified by NMR from maple syrup) 6 – 9 to purify (by chromatography) and characterize (by UFLC-MS/MS) the maple phenolic lignan-enriched standard (MaPLES).
the precise biochemical alter-ations accompanying the toxicity and therapy effects of realgar is lacking. Using a combined ultrafast liquid chro-matography (UFLC) coupled with ion trap time-of-flight mass spectrometry (IT-TOF/MS) and 1H NMR spectroscopy based metabolomics approach,
2016年3月24日 · UFLC-MS/MS Data for Compounds Identified in MaPLES by Comparison of Retention Times (tR) and Mass Spectral Data with Authentic Lignan Standards Previously Isolated and Identified (by NMR) from Maple Syrup8,9
UFLC–MS/MS method for simultaneous determination of six …
2013年4月10日 · Therefore, an efficient, sensitive and selective ultra fast liquid chromatography/tandem mass spectrometry method for the simultaneous determination of six sedative and hypnotic lignans (schisandrin, schisandrol B, schisantherin A, deoxyshisandrin, γ -schisandrin and gomisin N) of Schisandra chinensis (Turcz.)
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