This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, …

2024年12月25日 · UGT1A9 (UDP Glucuronosyltransferase Family 1 Member A9) is a Protein Coding gene. Diseases associated with UGT1A9 include Crigler-Najjar Syndrome, Type Iiand …

2025年2月19日 · UGT1A9 is the major isoform responsible for the glucuronidations of fraxetin in liver microsomes.

该基因编码一种 UDP-葡萄糖醛酸转移酶，一种葡萄糖醛酸化途径的酶，可将类固醇、胆红素、激素和药物等亲脂性小分子转化为水溶性、可分泌的代谢物。 该基因是编码多种 UDP-葡糖醛酸 …

UGT1A9主要表达于肝脏、肾脏，底物有毒物 (如酚类N-羟芳香胺，N-羟萘胺，蒽醌)内源性物质 (如雌激素，类固醇)和一些药物 (如地西泮、香豆素、麦考酚酸等)。

In the present study, the UDP-glucuronosyltransferase (UGT) 1A9 enzyme is identified as a PPARα and PPARγ target gene. UGTs catalyze the glucuronidation reaction, which is a major …

2024年12月10日 · This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, …

Title: UGT1A1 and UGT1A9 Are Responsible for Phase II Metabolism of Tectorigenin and Irigenin In Vitro. Genetic variants in CYP2A6 and UGT1A9 genes associated with urinary nicotine …

Results: We confirmed the presence of the -109 to -98 T10 polymorphism and found ten novel SNPs that generated a diversity of haplotypes in two independent populations. In a panel of 48 …

2022年12月23日 · 由位于染色体2q37上的UGT1A9基因编码的尿苷二磷酸葡萄糖醛酸转移酶，由530个氨基酸组成。 属UGT1A亚家族。