本产品是一种来自Saccharomyces cerevisiae的高活性的半胱氨酸蛋白酶 (cysteinyl protease) Ulp1 (Ubl-specific protease 1, ubiquitin-like protein-specific protease 1)基因片段的重组表达蛋白。 SUMO是一种泛素样蛋白 (Ubiquitin-like Protein)，是一种非常常见蛋白翻译后修饰 (post-translation modification, PTM)，对于蛋白的稳定性、生物学功能有重要的调节作用。

SUMO（小分子泛素修饰）蛋白酶1（Ulp1，来自酿酒酵母的Ubl特异性蛋白酶1）是一种高活性的半胱氨酸蛋白酶。Ulp1由于可以识别类泛素（UBL）蛋白SUMO（Smt3）的三级结构，而不是其氨基酸序列，因此具有高度特异性。

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SMT3 to its mature form and deconjugation of SMT3 from targeted proteins. Has an essential role in the G2/M phase of the cell cycle. Present with 377 molecules/cell in log phase SD medium.

SUMO Protease, also known as Ulp, is a recombinant fragment of ULP1 (Ubl-specific protease 1) from Saccharomyces cerevisiae. It is highly specific for the SUMO protein fusion, recognizing the tertiary structure of SUMO rather than an amino acid sequence.

此外1/2 ulp 通常用于衡量浮点数表示下近似的精度。举个例子。假设精度为1, 3.75可以近似为3或者4，分别对应的误差为0.75和0.25 (ulp)。 为了最小化误差选择近似为4，对应的误差 <1/2 ULP。

2025年2月8日 · Data show that Esc1 and Ulp1 help retain unspliced pre-mRNAs in the nucleus, and are essential for proper nuclear basket function, which includes mRNA surveillance and regulation of SUMO protein dynamics. Title: A nuclear envelope protein linking nuclear pore basket assembly, SUMO protease regulation, and mRNA surveillance.

德泰生物SUMO蛋白酶为使用E.coli表达经亲和纯化的重组蛋白酶，带有多聚His标签，便于融合蛋白切割后利用亲和层析去除蛋白酶。 融合蛋白SUMO标签剪切去除。 在1×SUMO Protease Buffer（50 mM Tris-HCl, pH 8.0, 1 mM DTT）中，30°C反应1h，剪切>85％的2 μg对照底物所需要的酶量定义为一个活性单位。 -80℃条件下可保存2年；-20°C条件下可保存6个月；避免反复冻融。 1. 酶切条件. 推荐4℃酶切过夜，使用者可以根据自己研究的目的蛋白进行摸索。 2. 酶切条 …

SUMO蛋白酶也被称为Ulp，作为一种高活性半胱氨酸蛋白酶，其是酿酒酵母中ULP1(Ubl特异性蛋 白酶1)的重组片段。 SUMO蛋白酶可以高度特异性地将重组融合蛋白中的SUMO切除，其识别对象是泛

The Ulp1 protease catalyzes two essential functions in the SUMO pathway: (1) processing of full-length SUMO to its mature form and (2) deconjugation of SUMO from targeted proteins. Selective reduction of the proteolytic reaction produced a covalent thiohemiacetal transition state complex between a Ulp1 C-terminal fragment and its cellular ...

Description SUMO Protease, also known as Ulp, is a recombinant fragment of ULP1 (Ubl-specific protease 1) from Saccharomyces cerevisiae. It is highly specific for the SUMO protein fusion, recognizing the tertiary structure of SUMO rather than an amino acid sequence.