U.S. Route 421 (US 421) in the U.S. state of Kentucky is a 250.536-mile-long (403.199 km) north–south United States highway that traverses twelve counties in the central and eastern parts of the state.

U.S. Route 421 (also U.S. Highway 421, US 421) is a diagonal northwest–southeast United States Numbered Highway in the states of North Carolina, Tennessee, Virginia, Kentucky, and Indiana. The highway runs for 941 miles (1,514 km) from Fort Fisher, North Carolina, to US 20 in Michigan City, Indiana.

U.S. Route 421 is a spur route of U.S. 21. It runs for 941 miles (1,514 km) from Michigan City, Indiana, at U.S. 20, to Fort Fisher in North Carolina.

U.S. Route 421 is a spur route of U.S. 21. It runs for 941 miles (1,514 km) from Michigan City, Indiana, at U.S. 20, to Fort Fisher in North Carolina.

This programming study was conducted to develop and to evaluate alternatives for improving US-421 in Franklin County, from the Top of Bald Knob Hill and to the intersection of US-421 with KY-12, which is also known as St. Johns Road.

The Kentucky Transportation Cabinet (KYTC) is in the design phase of a project to improve safety, geometry and traffic flow along US 421 from the Milton-Madison Bridge to the US 421 hill just south of Milton in Trimble County.

The existing US 421 corridor is a 2-lane roadway through rolling terrain with 9-foot travel lanes and 2-foot shoulders. Support economic development initiatives in Jackson County by opening up this low-income area. Improve access to jobs, hospitals, services, shopping, and schools in Berea, Richmond, and Lexington.

Kentucky and Indiana will apply for federal money to replace the narrow bridge carrying US 421 over the Ohio River between Madison, Indiana and Milton, Kentucky. If approved, the plan is demolish the current bridge and build a similar looking, wider bridge in …

Current US 421 Kentucky Road Conditions DOT Accident and Construction Reports KY-80 / State Highway 80 Road is closed from KY-451 (East) (KY-80) to KY-15 (KY-80).

2024年1月26日 · The meeting was a time to update community members about the reconstruction plan for 1.5mi of U.S. 421 in Harlan County near the Virginia state line.