Ursodeoxycholic acid (UDCA) is a secondary bile acid with cytoprotectant, immunomodulating, and choleretic effects. It reduces the cholesterol fraction of biliary lipids. 1 UDCA inhibits the …

2020年7月9日 · 该研究的一组试验在空肠处放置气囊人造肠梗阻，采集了给药250~750 mg 后气囊上方肠腔的样品；试验结果显示血浆UDCA 浓度在40~90 min 左右达到峰值，肠腔样品中已溶 …

熊去氧胆酸（ursodeoxycholic acids，UDCA）是治疗本病的首选药物。 为进一步规范PBC的诊断和治疗，中华医学会肝病学分会组织有关专家，在2015年版《原发性胆汁性肝硬化诊断和治 …

Tauroursodeoxycholic acid (TUDCA) is a taurine conjugated form of UDCA with higher hydrophilicity. TUDCA 750 mg/day showed similar biochemical efficacy and safety profile to …

The effects of ursodeoxycholic acid (UDCA, 750-1250 mg/day) were evaluated prospectively in 15 patients with primary sclerosing cholangitis (PSC). Five patients had associated inflammatory …

Ursodeoxycholic acid (3α, 7β-dihydroxy-5β-colonic acid; UDCA) is a hydrophilic bile acid that is currently increasingly used in the treatment of cholestatic disorders [83,84]. The first effects of …

View ursodeoxycholic acid information, including dose, uses, side-effects, pregnancy, breast feeding, contra-indications and monitoring requirements.

Ursodeoxycholic acid (UDCA) is a non-toxic, hydrophilic bile acid indicated for treatment of gallstones and primary biliary cirrhosis (PBC). 1 Endogenous bile acids are hepatically …

2021年10月26日 · We found that the therapeutic efficacy of UDCA in the treatment of DILI was beneficial with lower dose range of 250–500 mg/day as well as with 750–1,500 mg/day (up to …

2023年5月30日 · Herein, a novel gradient RP-HPLC method coupled to charged aerosol detection (CAD) was developed and validated for the simultaneous separation and quantification of the …