Molecular and cellular characterization of human renal cell carcinoma cell lines. Chromosome 17p deletions and p53 mutations in renal cell carcinoma. Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal …

2004年10月22日 · Glut-1 expression significantly decreased across all four methylated cell lines: UOK 108 expression decreased to 83% of the original, UOK 121 to 33%, UOK 127 to 67%, and UOK 143 to 63% (P < 0.05 in all cases). Glut-1 expression also decreased in 786–0, with expression after treatment down to 15% of control levels (P < 0.005). VEGF expression ...

2011年1月1日 · All 15 hit compounds tested also showed differential inhibition of cell proliferation in paired UOK-121 and UOK-121VHL cells as well as in UOK-127 and UOK-127VHL cells (Fig. 1). Because of its fluorescent nature, we chose one of the hit compounds, carminomycin I (CA), as a model to illustrate the utility of natural products in providing a novel ...

Human RCC cell lines A498 (HLA-A*02:01+), UOK127 (HLA-A*02:01+), and 769P (HLA-A*02:01−) were used as target cells. CTAG1Band luciferasegenes were introduced into the cell lines, and primary human T cells were engineered to express the cognate NY-ESO-1 antigen-specific T cell receptor.

2023年4月1日 · Knockdown of PD-L1 was tested in UOK-276 and 786-O cells and led to decreased expression levels of EMT transcription factors and increased epithelial markers. These data support the theory that sRCC arises from EMT …

Comparison of branching morphogenesis in two ccRCC VHL-methylated cell lines, UOK 108 and UOK 127, and the ccRCC VHLnegative but non-VHL–methylated 786 – 0 cell line. The cell lines are...

2022年5月17日 · The data in the five non-sarcomatoid ccRCC cell lines-RC2, CAKI-1, 786-0, RCC4, and RCC4/VHL-and in the four ccRCC with sarcomatoid differentiation-RCJ41T1, RCJ41T2, RCJ41M, and UOK-127-indicated that miR-17 and -19a were expressed at lower levels relative to miR-34a, -155, and -210.

2022年5月17日 · The data in the five non-sarcomatoid ccRCC cell lines—RC2, CAKI-1, 786-0, RCC4, and RCC4/VHL—and in the four ccRCC with sarcomatoid differentiation—RCJ41T1, RCJ41T2, RCJ41M, and UOK-127—indicated that miR-17 and -19a were expressed at lower levels relative to miR-34a, -155, and -210.

2012年8月1日 · Its IC50 value in pVHL-competent (VHL+/+) 786-OVHL, RCC4VHL, UOK-121VHL, and UOK-127VHL cells was found to be between 10 and 100 µM. We then proceeded to determine whether this level of activity was specific to CCRCC cells by testing VA against a panel of VHL+/+ non-CCRCC renal cancer cell lines.

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