2022年1月1日 · Koi herpesvirus (KHV) is a globally notifiable fish pathogen that causes disease in common carp and their varieties of koi carp and carp hybrids (Cyprinus carpio x Carassius auratus). The initial reported outbreaks of KHV disease (KHVD) came from Israel, the United States of America, and Germany in 1997–1998.

2020年6月15日 · Koi herpesvirus (KHV), also known as Cyprinid herpesvirus 3 (CyHV3) or carp interstitial nephritis gill necrosis virus, is a highly contagious viral pathogen of common carp and koi carp varieties. Mortality rates are influenced by the virulence of the strain of the virus, the age of the fish (younger fish are more affected than older fish), and ...

2020年7月1日 · In these tissues, KHV mRNA was detected which implements virus replication. No KHV mRNA was detected in healthy mucus‐covered skin without any injuries before the second or third dpi (Monaghan et al. 2015). After natural infection by immersion, KHV can be trapped by the mucus without any replication.

TOC summary: This virus is useful for fundamental and applied research. Keywords: Cyprinid herpesvirus 3, CyHV-3, koi herpesvirus, KHV, Alloherpesviridae, common carp, koi carp, fish, viruses, synopsis. The recently designated cyprinid herpesvirus 3 (CyHV-3) is an emerging agent that causes fatal disease in common and koi carp.

Different KHV lineages have clearly been identified, possible genomic changes during replication in different cell cultures at different temperatures but also in several hosts have been identified, a persistent stage of infection has been specified and it has been shown that infection with KHV is not host specific at all, but KHVD is.

2017年6月8日 · Worldwide koi herpesvirus (KHV) causes high mortalities in Cyprinus carpio L. aquaculture. So far, it is unknown how the different variants of KHV have developed and how they spread in the fish, but also in the environmental water bodies.

Acyclovir has been shown effective in vitro against KHV. This study aimed to evaluate the cytotoxicity of acyclovir and cidofovir to koi fin (KF1) cells, the efficacy of a single antiviral intracoelomic dose in a koi fingerling cohabitation challenge, and the pharmacokinetics of the effective antiviral.

2019年11月20日 · Koi herpesvirus disease (KHVD) is a disease of common carp, Cyprinus carpio, and its ornamental varieties that has had a significant effect on their culture since the mid- to late-1990s.

Koi herpesvirus disease (KHVD) is a herpesvirus infection (18) capable of inducing a contagious and acute viraemia in common carp (Cyprinus carpio) and varieties such as koi carp and ghost carp (16). 2. Disease information. 2.1. Agent factors. 2.1.1. Aetiological agent, agent strains.

2020年2月19日 · Different KHV lineages have clearly been identified, possible genomic changes during replication in different cell cultures at different temperatures but also in several hosts have been...