2024年7月6日 · Immune engineering and modulation are the basis of a novel but powerful tool to treat immune diseases using virus-like particles (VLPs). VLPs are formed by the viral capsid …

2023年8月19日 · In this review, we summarize the VLP cancer vaccines successfully licensed or under development for the prevention of cancer caused by viral infections, as well as the VLP …

2024年12月12日 · VLP-based mucosal vaccines offer a compelling strategy for controlling infectious diseases that enter the body through mucosal surfaces. The ability of VLPs to carry …

Virus-like particles (VLPs) are self-assembled nanoparticles whose intrinsic properties, such as heterogeneity, and highly ordered structural organization are exploited to prepare vaccines; …

VLP from the foot-and-mouth disease virus (FMDV), which was loaded with the anticancer drug doxorubicin (DOX), can deliver the drug into HeLa cells via the RGD motif binding to the …

Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating epitopes, …

2010年5月2日 · We chemically coupled PvTRAP to VLPs derived from the cucumber mosaic virus fused to a universal T-cell epitope of the tetanus toxin (CMVtt), formulated with MCT and …

2023年3月31日 · VLPs produced using recombinant protein expression systems can stimulate strong B- and T-cell immune responses, have been shown to exhibit self-adjuvanting abilities …

2024年6月8日 · Various immunization approaches revealed that pCap3-Cap2E VLP vaccines were capable of activating high PCV3 Cap-specific antibody levels and effectively neutralizing …

2021年8月18日 · In this study, we developed SARS-CoV-2 virus-like particles (VLPs) containing the full length of spike (S) glycoprotein (S full), S1, or S2 together with the influenza matrix …