Hepatic veno-occlusive disease (VOD) or sinusoidal obstruction syndrome (SOS) is a rare complication characterized by hepatomegaly, right-upper quadrant pain, jaundice, and ascites, occurring after high-dose chemotherapy, hematopoietic stem cell ...

Hepatic veno-occlusive disease (VOD) is a non-thrombotic obliteration of the lumina of small intrahepatic veins. VOD has been reported after exposure to a wide variety of pathogens. It has been suggested that the chemoradiotherapy used as the conditioning regimen for bone marrow transplant (BMT) is …

2024年2月22日 · Hepatic sinusoidal obstruction syndrome (SOS), also called veno-occlusive disease (VOD), is a systemic endothelial disease that typically presents in the days or weeks after hematopoietic cell transplantation (HCT) with refractory thrombocytopenia, hepatomegaly, ascites, and jaundice, and it can rapidly progress to multiorgan dysfunction and death.

2023年4月24日 · Sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD; referred to as SOS/VOD hereafter) is a life-threatening complication occurring after...

Hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome, is a major complication of hematopoietic stem cell transplantation and it carries a high mortality. Prophylaxis for hepatic VOD is commonly given to transplant recipients from the start of conditioning through the early weeks of transplant.

2019年10月1日 · Commissioned by the EBMT, a global SOS/VOD Task Force was developed to help identify and address the key challenges in the prophylactic, preemptive, and curative treatment for SOS/VOD in adult...

Hepatic veno-occlusive disease (VOD) or sinusoidal obstructive syndrome (SOS) is a disorder characterised by obstruction of small intra-hepatic venules and damage to the surrounding centrilobular hepatocytes and sinusoids. It occurs principally as a complication of chemo-irradiation therapy, particularly following BMT.

2015年3月23日 · Sinusoidal obstruction syndrome or veno-occlusive disease (SOS/VOD) is a potentially life-threatening complication of hematopoietic SCT (HSCT). This review aims to...

Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .

2015年12月12日 · Hepatic veno-occlusive disease (VOD) is a common complication of the chemotherapeutic conditioning used in preparation for bone marrow transplant. In severe cases, VOD can cause multiorgan failure, leading to death in approximately 80% of patients.