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Population-based prevalence and mutational landscape of von
2023年10月16日 · Von Willebrand disease (VWD) is a common bleeding disorder caused by mutations in the von Willebrand factor gene (VWF). The true global prevalence of VWD has not been accurately established.
von Willebrand disease - Nature Reviews Disease Primers
2024年7月25日 · von Willebrand disease (VWD) is the most common inherited bleeding disorder. The disorder is characterized by excessive mucocutaneous bleeding. The most common bleeding manifestations of this...
Geographic Distribution of Persons with von Willebrand Disease
2023年6月5日 · This is archived content from the CDC website. The information here may be outdated and links may no longer function. Go to CDC Home for all other recent information.
Entry - #193400 - VON WILLEBRAND DISEASE, TYPE 1; VWD1
Von Willebrand disease is the most common inherited bleeding disorder. It is characterized clinically by mucocutaneous bleeding, such as epistaxis and menorrhagia, and prolonged bleeding after surgery or trauma. The disorder results from a defect in platelet aggregation due to defects in the von Willebrand factor protein.
Diagnosis and Disease Burden of Von Willebrand Disease in a …
2024年11月5日 · Introduction: Von Willebrand disease (VWD) is the most common inherited bleeding disorder, affecting up to 1% of the population. Patients with VWD experience excessive bleeding, but bleeding types, severity, and frequency vary. Although improved recently, diagnosis continues to be delayed, which interferes with effective management.
全国确诊仅600人!血管性血友病创新药物获批 - 百家号
2024年8月5日 · 血管性血友病(vwd)是一种遗传性出血性疾病,患者由于基因突变引起血浆中的血管性血友病因子(vwf)数量减少或质量异常,从而自幼常于皮肤和黏膜发生出血事件,严重时甚至会发生内脏出血进而危及生命。
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Perils, Problems, and Progress in Laboratory Diagnosis of Von ...
Diagnosis of von Willebrand disease (VWD) merits consideration of personal and family history of bleeding symptoms along with confirmatory laboratory testing. Because the latter yields quantifiable results, over-reliance on a laboratory diagnosis may occur. However, existing tests for VWD contain potential sources for error.
Entry - #277480 - VON WILLEBRAND DISEASE, TYPE 3; VWD3
2010年12月27日 · A number sign (#) is used with this entry because von Willebrand disease (VWD) type 3 is caused by homozygous or compound heterozygous mutation in the gene encoding von Willebrand factor (VWF; 613160), which maps to chromosome 12p13.