Endothelial cell ADAMTS-13 and VWF: production, release, and VWF …
2009年12月3日 · Human umbilical vein endothelial cell (HUVEC)-released ADAMTS-13 (a disintegrin and metalloprotease with thrombospondin repeats) and HUVEC-secreted von …
血管性血友病因子 (VWF) 调节血管生成：来自血管性血友病患者和 VWF …
Inhibition of VWF expression in human umbilical vein EC (HUVEC) with specific siRNA resulted in increased in vitro angiogenesis on Matrigel, proliferation and migration. Mechanism studies …
Expression of von Willebrand factor (vWF) in HuVECs. The vWF …
To understand the molecular mechanism of hemorrhagic tendency represented in hemorrhagic fever with renal syndrome (HFRS), the effect of Hantaan virus (HTNV) on the von Willebrand …
Regulation of von Willebrand Factor Gene in Endothelial Cells …
2019年1月25日 · We studied the regulation of a highly endothelial-specific gene, von Willebrand factor (VWF), in induced pluripotent stem cells generated from primary endothelial cells …
内皮细胞 ADAMTS-13 和 VWF：生产、释放和 VWF 串裂解,Blood
HUVEC ADAMTS13 mRNA 表达约为 VWF 单体亚基表达的 1:100。与储存在 Weibel-Palade 体内并响应细胞刺激迅速分泌的多聚体 VWF 不同，ADAMTS-13 直接从高尔基体释放到细胞外 …
Tissue factor: A potent stimulator of Von Willebrand factor …
2016年9月20日 · We investigated the effect of inflammatory and thrombotic stimuli and the combination thereof on the release of VWF and its cleavage protease ADAMTS13 by human …
VWF and ADAMTS13 behavior in estradiol-treated HUVEC
Incubation of HUVEC with E2 resulted in a significantly increased expression of VWF and ADAMTS13 mRNA. ADAMTS13 gene inactivation upregulates release and intracellular VWF …
[摘要]目的:探讨过表达血管性血友病因子(vwf)对人脐静脉内皮细胞(huvecs)增殖、迁移、侵袭、凋亡及成管能力的影响。 方法:设计构建5种过表达vwf的质粒crispra载体,将huvecs分为实验组(5 …
Regulated von Willebrand factor (vWf) secretion is restored by pro-vWf ...
2000年1月10日 · The processing of vWf has been mostly studied in cultured human umbilical vein endothelial cells (HUVEC). vWf is synthesized as a large precursor, pro-vWf, which undergoes …
Development of a dual hybrid AAV vector for endothelial-targeted ...
2021年1月17日 · Von Willebrand disease (VWD), the most common inherited bleeding disorder in humans, is caused by quantitative or qualitative defects in von Willebrand factor (VWF). VWD...