2018年5月1日 · Inhibition of Rho activation is a potential treatment for injuries such as traumatic SCI. VX-210, an investigational agent, inhibits Rho. When administered extradurally after …

2018年10月25日 · Vertex has halted development of VX-210 after a phase 2b acute spinal cord injury trial failed an interim analysis. The lack of efficacy seen in the phase 2b is another, …

2023年5月1日 · After SCI, Rho activation contributes to collapse of axonal growth cones, failure of axonal regeneration, and neuronal loss. This randomized, double-blind, placebo-controlled …

VX-210, formerly referred to as BA-210 or Cethrin, is a cell-permeable derivative of the bacterial enzyme, C3 transferase, that inhibits Rho activity through covalent modification and therefore …

2021年8月1日 · VX-210 is a cell-permeable derivative of a bacterial enzyme, C3 transferase, that inhibits Rho activity through covalent modification and therefore can potentially block Rho …

VX-210, formerly referred to as BA-210 or Cethrin, is a cell- permeable derivative of the bacterial enzyme, C3 transferase, that inhibits Rho activity through covalent modification and therefore

2022年6月22日 · VX-210, formerly referred to as BA-210 or Cethrin, is a cell-permeable derivative of the bacterial enzyme, C3 transferase, that inhibits Rho activity through covalent modification …

2021年8月1日 · After SCI, Rho activation contributes to collapse of axonal growth cones, failure of axonal regeneration, and neuronal loss. This randomized, double-blind, placebo-controlled …

2016年1月21日 · 本研究的目的是确定 vx-210 在急性外伤性颈脊髓损伤受试者中的疗效和安全性。 次要目标包括具体评估 vx-210 对脊髓损伤后神经恢复和日常功能的影响。。临床试验注册。 …

2016年2月12日 · Vertex Standard - VX-210A VHF/UHF Portable Radios. Designed to be lightweight, rugged, and feature rich, the VX-210A is the right radio for almost all applications. …