2023年10月1日 · Viable but nonculturable (VBNC) cells are characterized by their loss of culturability, ability to maintain a nonculturable state, and potential to resuscitate. The formation of VBNC cells can occur under a wider range of stress conditions, many of which are moderate and long-term in nature.

Viable but nonculturable (VBNC) bacteria refers as to bacteria that are in a state of very low metabolic activity and do not divide, but are alive and have the ability to become culturable once resuscitated.

Many bacterial species have been found to exist in a viable but non-culturable (VBNC) state since its discovery in 1982. VBNC cells are characterized by a loss of culturability on routine agar, which impairs their detection by conventional plate ...

摘要: 有活力但不可培养 (viable but non-culturable，VBNC)状态是细菌遭遇逆境时进入的一种特殊状态，该状态下的菌体在条件适宜时可复苏并恢复其致病性，被认为是细菌躲避不良环境的一种生存策略。 VBNC状态菌体对人类医学和工农业生产具有巨大的潜在威胁，开展关于VBNC状态的检测及诱导、复苏及其机制研究可为减少或避免该状态细菌的危害提供理论基础。 本文简要综述了细菌VBNC状态在诱导、复苏及致病性等方面的研究进展，并结合本实验室及国内外相关团队近 …

2024年10月21日 · In this present review, we mainly focus the VBNC state of Vibrios and other human bacterial pathogens. Exposure to several factors like nutrient depletion, temperature fluctuation, changes in salinity and oxidative stress, antibiotic and other chemical stress can induce the cells to VBNC state.

Viable but nonculturable (VBNC) cells are characterized by their loss of culturability, ability to maintain a nonculturable state, and potential to resuscitate. The formation of VBNC cells can occur under a wider range of stress conditions, many of …

2017年12月21日 · Persister and viable but non-culturable (VBNC) cells are two important clonal bacterial subpopulations that can survive antibiotic treatment. Both persister and VBNC cells pose a serious threat to human health.

What are the optimal methods for determining cellular viability to differentiate viable cells (culturable and VBNC cells) from nonviable cells (hol-low but membrane-enclosed and dead cells), considering the recent studies which suggest that an intact membrane does not always indicate a viable cell?

2023年12月25日 · This review explores the concept of the VBNC state, providing insights into the beneficial bacteria known to employ this strategy. The investigation covers different chemical and physical factors that can induce the latency state, cell features, and gene expression observed in cells in the VBNC state.

Stimulated by a variety of environmental, biological, or chemical stimuli, VBNC cells may resuscitate and recover their cell division ability with an elevated metabolic level, as well as pathogenicity and cell morphology (Figure 1).