2000年1月17日 · Here we report a system that induces the expression of the bax gene safely by adenovirus-mediated gene cotransfer. Briefly, the system involves an adenoviral vector …

2001年9月18日 · A second-generation adenoviral vector was constructed with the modified prostate-specific probasin promoter, ARR2PB, directing expression of an HA-tagged Bax gene …

Here we report a system that induces the expression of the bax gene safely by adenovirus-mediated gene cotransfer. Briefly, the system involves an adenoviral vector containing a …

Objective To clone early growth response-1 (EGR1) gene and BCL2-associated X protein (Bax) gene, construct their co-expression vector pGL3/EGR1-Bax, and transfect it into cells of...

Our study showed for the first time that BAX was associated with chromatin in vitro. Next, we used gain and loss of function approaches to decipher the potential role of nuclear BAX in non …

2019年6月1日 · Bax is able to interact with the MOM with both its termini, making it inherently difficult to express in E. coli. In this study, we present a novel approach to express and purify …

Our results indicate that a bax recombinant ad-enoviral vector causes cell death mediated via an apoptotic path-way in multiple cervical cancer cell lines and primary cervical cancer cells. …

Attempts to express a truncated form of murine Bax in the periplasm by using an expression vector that attached the OmpA signal sequence to the protein failed to alleviate this toxicity. In …

2001年4月27日 · Here we assess whether BAK is required for tBID-induced apoptosis of intact, whole cells by using a retroviral vector to express tBID in murine embryonic fibroblasts (MEFs).

2020年6月12日 · Here we describe the development of a highly sensitive in vitro biopotency assay for BAX 335, an AAV8-based hemophilia B gene therapy vector expressing FIX Padua …