2022年7月1日 · In this paper, we review the most recent studies on VGF gene structure, transcriptional regulation, protein processing, expression distribution, and potential receptors. …

VGF and VGF-derived peptides have been repeatedly identified in well-powered and well-designed multi-omic studies as dysregulated in neurodegenerative and psychiatric diseases. …

2021年10月27日 · In this review, we summarize recent studies that identify the physiological roles of VGF and VGF-derived peptides, their dysregulation in and potential use as …

从参与阿尔茨海默病发病机制的 537 个基因列表中，vgf 被阿尔茨海默病加速药物合作伙伴关系强调为最受关注的潜在治疗靶点。与对照组相比，阿尔茨海默病患者的脑组织和脑脊液样本中 …

vgf 神经生长因子诱导型： 该基因在神经内分泌细胞亚群中特异性表达，并被神经生长因子上调。 该基因的结构组织与大鼠基因相似，翻译区和非翻译区均显示出与大鼠基因高度的序列相似性。

2021年10月27日 · VGF and VGF-derived peptides have been repeatedly identified in well-powered and well-designed multi-omic studies as dysregulated in neurodegenerative and …

2017年11月21日 · Here, we show that VGF (non-acronymic), which is robustly regulated by BDNF/TrkB signaling, is downregulated in hippocampus (male/female) and upregulated in …

2015年2月1日 · VGF peptides have been associated with a number of neuroendocrine roles, and in this review, we aim to describe these roles to highlight the importance of VGF as therapeutic …

Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry. This gene is specifically expressed in a subpopulation of neuroendocrine …

2011年12月1日 · We review the VGF (non acronymic) multifunctional peptide precursor. VGF mRNA is regulated by neurotrophins, synaptic activity, homeostatic and other stimuli. …