2010年5月18日 · Members of the Wall-Associated Kinase (WAK) family are candidate receptors of OGs, due to their ability to bind in vitro these oligosaccharides. Because lethality and redundancy have hampered the study of WAKs by reverse genetics, we have adopted a chimeric receptor approach to elucidate the role of Arabidopsis WAK1.

近日，四川农业大学 陈学伟教授 团队应 Stress Biology 邀请撰写了关于细胞壁与植物免疫的综述文章“ Cell wall associated immunity in plants ”，详细评述了近年来细胞壁在植物免疫调控方面的研究进展。 细胞壁是一个高度复杂的动态网状结构，主要由 纤维素 、 半纤维素 和 果胶 等组成。 在病原菌侵染过程中往往会直接破坏细胞壁的完整性，而植物在感知细胞壁损伤后，通常会激发一系列的防御反应，包括植物细胞壁化学成分及结构的改变。 该研究详细介绍了包括纤维素，半 …

2024年12月12日 · Using a combination of immune assays for early and late pattern-triggered immunity, we show that WAKs are dispensable for OG-induced signaling and immunity, indicating that they are not bona fide OG receptors. Plants are exposed to myriad potential pests and pathogens, against which they have evolved sophisticated defense mechanisms.

细胞壁连接的类受体激酶(wak)是一类特殊的植物类受体激酶, 与细胞壁中的果胶共价交联. 在结构上, wak分为胞外域、跨膜域和胞内激酶结构域, 胞外域中存在保守的egf重复序列.

2023年3月10日 · Wall-associated kinase (WAK) family proteins have been shown to interact with pectin and transmit defense and developmental signals in plant cells (35–37). There are five WAK family genes in Arabidopsis that are located next to each other on chromosome 1.

2024年4月15日 · 22 (WAK) family have been shown to bind pectin and OGs, and were previously proposed as OG 23 receptors. However, unambiguous genetic evidence for the role of WAKs in OG responses is 24 lacking. Here, we investigated the role of Arabidopsis WAKs in OG perception using a novel 25 deletion mutant of the clustered WAK family.

2012年5月7日 · WAKs are required for cell expansion, are involved in the pathogen response, and their expression is activated by numerous environmental stimuli. Recent work supports the idea that WAKs are receptors for both pectin in the cell wall, and for pectin fragments, oligogalacturonic acids (OGs), generated during some pathogen attacks.

2016年1月16日 · Receptor-like kinases are well-known to play key roles in disease resistance. Among them, the Wall-associated kinases (WAKs) have been shown to be positive regulators of fungal disease resistance in several plant species. WAK genes are often transcriptionally regulated during infection but the pathways involved in this regulation are not known.

Members of the Wall-Associated Kinase (WAK) family are candidate receptors of OGs, due to their ability to bind in vitro these oligosaccharides. Because lethality and redundancy have hampered the study of WAKs by reverse genetics, we have adopted a chimeric receptor approach to elucidate the role of Arabidopsis WAK1.

细胞壁连接的类受体激酶（WAK）是一类特殊的植物类受体激酶，与细胞壁中的果胶共价交联．在结构上，WAK分为胞外域、跨膜域和胞内激酶结构域，胞外域中存在保守的EGF重复序列．WAK以多基因家族形成存在，其表达模式具有组织特异性，主要在叶、茎中表达，在功能上参与病原菌反应、细胞伸长调控、铝胁迫反应等．WAK1在细胞外与富含甘氨酸的蛋白质AtGRP3特异结合，在胞内与蛋白磷酸酶KAPP结合并形成约500kD的AtGRP3-WAK1-KAPP复合体．植物 …