The molecular basis of regulation of bacterial capsule assembly by Wzc …
2021年7月16日 · Gram-negative species couple polymerization with translocation across the periplasm and outer membrane and the master regulator of the system is the tyrosine …
Wza gene knockout decreases Acinetobacter baumannii virulence …
Expression levels of wzb, wzc and wzi were decreased in wza knockout strains. The antioxidant capacity of Wza knockout bacteria was only slightly decreased. Complementation of the wza …
Structural basis for the recognition of the bacterial tyrosine kinase ...
The structure of the Wzb–Wzc CDΔC complex determined here not only reveals key structural features that enable molecular recognition between these two species but also provides a …
wzb磷酸酶和wzc激酶相互作用的合理靶向抑制了 ... - X-MOL
EPS的合成及其输出受细菌Wza-Wzb-Wzc系统的调节。 Wzc表现出自磷酸化蛋白酪氨酸激酶活性，而Wzb是一种蛋白酪氨酸磷酸酶。 Wzb介导Wzc的去磷酸化。
Rational targeting of Wzb phosphatase and Wzc kinase …
2020年6月1日 · Wzc exhibits auto-phosphorylation protein tyrosine kinase activity, while Wzb is a protein tyrosine phosphatase. Wzb mediates dephosphorylation of Wzc. Dephosphorylated …
The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb …
2019年1月23日 · The results obtained demonstrate that Wzc (Sll0923) and Wzb (Sll0328) are involved in the production of EPS, influencing both the amount and the composition of …
Rational targeting of Wzb phosphatase and Wzc kinase …
EPS synthesis and its export is regulated by the bacterial Wza-Wzb-Wzc system. Wzc exhibits auto-phosphorylation protein tyrosine kinase activity, while Wzb is a protein tyrosine …
Functional Analysis of Conserved Gene Products Involved in …
In this biosynthesis pathway, Wza, Wzb, and Wzc homologues are required for surface expression of wild-type CPS or EPS. Multimeric complexes of Wza in the outer membrane are …
The Solution Structure of Escherichia coli Wzb Reveals a Novel ...
2006年7月14日 · Low molecular weight protein-tyrosine phosphatases (LMW-PTPs) are small enzymes that ubiquitously exist in various organisms and play important roles in many …
Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, …
Two proteins of Escherichia coli, termed Wzc and Wzb, were analyzed for their capacity to participate in the reversible phosphorylation of proteins on tyrosine. First, Wzc was …