Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40k Da in size that in humans is encoded by the CHI3L1 gene. [5][6][7] The …

YKL-40 is a biomarker for inflammatory diseases’ diagnosis and prediction. YKL-40 concentration increases with age and has variations in healthy population. YKL-40 is convincing in …

YKL-40, a member of 'mammalian chitinase-like proteins', is secreted by macrophages, neutrophils, chondrocytes, endothelial-, vascular smooth muscle-, and cancer cells. High …

壳酶蛋白，全称：壳多糖酶 3 样蛋白 1（Chitinase-3-Like protein 1，CHI3L1，又名YKL-40）是一种含383个氨基酸，分子量42.6KD的单体糖基化蛋白，为糖基水解酶家族成员之一，在炎症和 …

This review will discuss the potential of YKL-40 in the pathogenesis of autoimmune and rheumatic diseases, such as rheumatoid arthritis, psoriasis, systemic lupus erythematosus, Behçet …

2024年2月15日 · YKL-40 or Chitinase-3-Like Protein 1 (CHI3L1) is a highly conserved glycoprotein that binds heparin and chitin in a non-enzymatic manner. It is a member of the …

2023年11月6日 · YKL-40, also known as human cartilage glycoprotein 39 or chitinase-3 like protein 1, contains highly conserved chitin-binding domains. It lacks chitinase or hydrolase …

2020年12月19日 · 这些研究结果表明，YKL-40是昼夜节律紊乱和阿尔茨海默病之间的可能联系，靶向这种蛋白的疗法可能会减缓这种疾病的进程。 论文通讯作者、华盛顿大学圣路易斯医 …

YKL-40 is an inflammatory glycoprotein involved in endothelial dysfunction by promoting chemotaxis, cell attachment and migration, reorganization and tissue remodelling as a …

YKL-40 is a secreted glycoprotein that can promote invasion, angiogenesis and inhibit apoptosis, and was highly expressed in a variety of tumours. In this paper, we investigated the impacts of …