14-3-3 protein epsilon is a protein that in humans is encoded by the YWHAE gene. [5] This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding …

2024年12月25日 · YWHAE (Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon) is a Protein Coding gene. Diseases associated with YWHAE …

The YWHAE gene provides instructions for making the 14-3-3 epsilon protein, which is part of the large 14-3-3 protein family. Learn about this gene and related health conditions.

2024年1月26日 · 14–3-3ε, a member of the 14–3-3 protein family, is encoded by the YWHAE gene. In humans, YWHAE is located on the 17 th chromosome and involved in cell adhesion, …

5 天之前 · YWHAE is closely related to several human diseases and acts as a molecular scaffold for malignant transformation. However, whether YWHAE promotes HB development remains …

Results: We report a series of 10 individuals with heterozygous loss-of-function YWHAE variants (3 single-nucleotide variants and 7 deletions <1 Mb encompassing YWHAE but not …

YWHAE (14-3-3ε) protein levels are considered to be a reliable biomarker for neurodegeneration. The YWHAE protein interacts both directly and indirectly with human immunodeficiency virus …

YWHAE expression was associated with tumor size, lymph node metastasis, and poor patient survival in patients with breast cancer. YWHAE overexpression significantly increased the …

2016年12月20日 · YWHAE may act as a negative regulator of the cyclin CDC25B, which is a transcriptional target of MYC oncogene. The understanding of YWHAE role and its targets is …

results support YWHAE being a risk gene for Major Depressive Disorder in the Han Chinese population. YWHAE silencing induces cell proliferation, invasion and migration through the up …

YWHAE is a prognostic marker in Breast invasive carcinoma, Kidney renal clear cell carcinoma, Lung adenocarcinoma

2022年10月10日 · Here, we report clinical manifestations of 15 patients with clear dose-dependent loss-of-function variants in YWHAE, 5 of which are patients with variants affecting …

The YWHAE gene provides instructions for making the 14-3-3 epsilon protein, which is part of the large 14-3-3 protein family. Proteins in this family attach (bind) to other proteins that are …

2022年1月28日 · To understand the relationship between YWHAE, NUTM2A, and NUTM2B gene rearrangement/fusion and malignant tumor, YWHAE-FAM22 fusion gene/translocation and …

2025年2月8日 · The protein YWHAE (14-3-3 epsilon) in spermatozoa is essential for male fertility. Activation of innate immunity by 14-3-3 epsilon, a new potential alarmin in osteoarthritis. Rod …

2024年5月13日 · YWHAE overexpression significantly reduced the expression level of SCN5A mRNA and sodium current density, whereas YWHAE knockdown significantly increased …

Interestingly, the strongest evidence for epistasis was detected for the YWHAE gene, whose product, 14‐3‐3ϵ, is known to mainly form heterodimers with many other 14‐3‐3 proteins. …

2024年11月27日 · Comprehensive analysis of the function of helicobacter-associated ferroptosis gene YWHAE in gastric cancer through multi-omics integration, molecular docking, and …

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