We have analysed the contribution of the Msn2/4 transcription factors and the Ras-cAMP-protein kinase A (PKA) pathway to the control of the yeast H2O2 response. Strains deleted for MSN2 and MSN4 are hypersensitive to H2O2, although they can still adapt to this oxidant.

2002年6月28日 · We have analysed the contribution of the Msn2/4 transcription factors and the Ras-cAMP-proteine kinase A (PKA) pathway to the control of the yeast H 2 O 2 response. Strains deleted for MSN2 and MSN4 are hypersensitive to H 2 …

In this review, we focus on the role of hydrogen peroxide, H 2 O 2, as a signaling molecule regulating protein synthesis at different levels, including transcription and various parts of the translation process, e.g., initiation, elongation, termination and ribosome recycling.

(i) CCP is a key enzyme of H 2 O 2 detoxification in yeasts. (ii) Catalase can effectively compete with mitochondrial CCP for hydrogen peroxide only if hydrogen peroxide is generated at the site where catalase is located, namely in the peroxisomes. These references are in PubMed. This may not be the complete list of references from this article.

1995年2月20日 · Adaptive responses to the oxidative stress of hydrogen peroxide (H2O2) were studied in the yeast Saccharomyces cerevisciae strain RZ53. Our results show that the growth of naive cells is readily arrested by H2O2 challenge.

reaction can be retrieved from a Lineweaver-Burk plot. As H2O 2 is a toxic compound obtained as a by-product in many reactions in living organi. ms, it is useful to understand its degradation process. In this experiment, the reaction rate.

2020年10月16日 · The function of catalases A and T from the budding yeast Saccharomyces cerevisiae (ScCta1 and ScCtt1) is to decompose hydrogen peroxide (H 2 O 2) to mitigate oxidative stress. Catalase orthologs are widely found in yeast, suggesting that scavenging H 2 O 2 is crucial to avoid the oxidative damage caused by reactive oxygen species (ROS).

2008年11月1日 · In yeast cells, the thioredoxin and glutaredoxin systems participate in such redox regulation in different cell compartments, and interplay exists between both systems. In this context, glutaredoxins with monothiol activity initially characterised in Saccharomyces cerevisiae may display specific regulatory functions at the mitochondria and nuclei.

Hydrogen peroxide is breaks down into water and oxygen. That’s why it’s stored in dark containers: to slow this process down. Adding the yeast to the hydrogen peroxide helps this breaking-down process occur much faster. As the process progresses, the dishwashing soap catches the oxygen that is released by the peroxide.

2000年10月2日 · We provide biochemical and genetic evidence that, in response to H 2 O 2, Yap1 is activated by oxidation and deactivated by enzymatic reduction with Yap1‐controlled thioredoxins, thus providing a mechanism for autoregulation. Two cysteines essential for Yap1 activation by H 2 O 2 are likely to form a disulfide bond upon oxidation.