YME1L1 - Wikipedia
YME1L1 consists of 716 amino acids and is highly similar to all mitochondrial AAA proteases and in particular to yeast Yme1p. Three different domains are identified via sequence analysis, …
YME1L1 Gene - GeneCards | YMEL1 Protein | YMEL1 Antibody
2024年12月25日 · YME1L1 (YME1 Like 1 ATPase) is a Protein Coding gene. Diseases associated with YME1L1 include Optic Atrophy 11 and Autosomal Recessive Isolated Optic …
线粒体蛋白酶Yme1L在线粒体动力学中的作用及分子机制_百度百科
线粒体蛋白酶Yme1L是由核编码然后输入定位到线粒体的ATP 依赖性的蛋白酶，它是线粒体内膜中线粒体蛋白质量调控的重要蛋白，其很多生物学功能特别是在线粒体动力学中的功能和作用机 …
Nature：脂类信号重塑线粒体蛋白稳态的新机制,YME1L与肿瘤发生 …
近年来研究发现，定位于线粒体内膜的i-AAA蛋白酶YME1L能通过调节OPA1实现对线粒体融合和分裂的控制，其缺失会导致细胞代谢异常。 然而，YME1L在线粒体蛋白稳态调控中的作用仍 …
Lipid signalling drives proteolytic rewiring of mitochondria by YME1L
2019年11月6日 · YME1L degrades mitochondrial protein translocases, lipid transfer proteins and metabolic enzymes to acutely limit mitochondrial biogenesis and support cell growth....
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance ... - PubMed
2014年3月17日 · Constitutive OPA1 cleavage by YME1L and OMA1 at two distinct sites leads to the accumulation of both long and short forms of OPA1 and maintains mitochondrial fusion. …
Nature | 脂类信号重塑线粒体蛋白稳态的新机制Nature | 脂类信号 …
近年来研究发现，定位于线粒体内膜的i-AAA蛋白酶YME1L能通过调节OPA1实现对线粒体融合和分裂的控制，其缺失会导致细胞代谢异常 【2】。 然而，YME1L在线粒体蛋白稳态调控中的 …
Targeting the mitochondrial protein YME1L to inhibit ... - Nature
2024年5月20日 · YME1L silencing impaired mitochondrial functions in osteosarcoma cells, causing mitochondrial depolarization, oxidative injury, lipid peroxidation and DNA damage as …
10730 - Gene ResultYME1L1 YME1 like 1 ATPase [ (human)]
2025年1月4日 · YME1L1 was identified as the first NUMT (nuclear mtDNA) suppressor gene in human and demonstrate that inactivation of YME1L1 induces migration of mtDNA to the …
Regulation of mitochondrial plasticity by the i-AAA protease YME1L
2020年5月26日 · The i-AAA protease YME1L, an ATP-dependent proteolytic complex in the mitochondrial inner membrane, coordinates mitochondrial biogenesis and dynamics with the …