ZSCAN4 Gene - GeneCards | ZSCA4 Protein | ZSCA4 Antibody
2024年12月25日 · The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying …
ZSCAN4 facilitates chromatin remodeling and promotes the
2020年6月7日 · In this study, we investigate the role of Zinc finger and SCAN domain containing 4 (ZSCAN4) in human head and neck squamous cell carcinoma (HNSCC). The murine Zscan4 …
Zscan4 binds nucleosomal microsatellite DNA and protects
2020年3月20日 · Zscan4-associated microsatellite regions are characterized by low nuclease sensitivity and high histone occupancy. In vitro, Zscan4 binds nucleosomes and protects them …
ZSCAN4在早期胚胎及多能干细胞中的作用及调节机制
ZSCAN4能够调控早期胚胎发育过程,在合子基因组激活(zygotic genome activation, ZGA)期间通过促进DNA损伤修复和纠正染色体异常,以维持植入前胚胎的基因组和染色体完整性。
Zscan4 mediates ubiquitination and degradation of the …
2024年12月20日 · Zscan4 exhibits burst expression in 2C embryos and 2C-like cells. Here, we show that Zscan4 mediates chromatin remodeling to promote the chromatin accessibility for …
Zscan4 regulates telomere elongation and genomic stability in
2010年3月24日 · We previously identified Zscan4 as a specific marker for two-cell embryo and ES cells. Here we show that Zscan4 is involved in telomere maintenance and long-term genomic …
A Comprehensive Review on the Role of ZSCAN4 in Embryonic …
ZSCAN4 is a transcription factor that plays a pivotal role during early embryonic development. It is a unique gene expressed specifically during the first tide of de novo transcription during the …
Zscan4 binds nucleosomal microsatellite DNA and protects …
2020年3月20日 · Zinc finger protein Zscan4 is selectively expressed in mouse two-cell (2C) embryos undergoing zygotic genome activation (ZGA) and in a rare subpopulation of …
Zscan4: a novel gene expressed exclusively in late 2-cell ... - PubMed
2007年7月15日 · Utilizing DNA microarray data, we looked for genes that are expressed only during ZGA and found Zscan4, whose expression is restricted to late 2-cell stage embryos. …
ZSCAN4 zinc finger and SCAN domain containing 4 [ (human)]
2025年2月8日 · The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular …