CCL6 is chemotactic for monocytes, macrophages, and T cells and is present in a variety of chronic inflammatory disorders. High expression of CCL6 has been found in the cerebellum …

2006年5月19日 · Antibodies specific for CC-chemokine ligand 3 (CCL3) or CCL4 inhibited the accumulation of OT-I T cells in lymph nodes containing activated OT-II T cells.

2007年10月15日 · Only 1.6% of total NK cells and 1.8% of total CD8 + T lymphocytes were positive for IFN-γ in CCL6 Tg mice (Fig. 10, B and C). Other cell types such as macrophages, …

2024年5月2日 · Overall, our results indicate that macrophages, like naive T cells (Extended Data Fig. 10), can differentiate into distinct subsets that express specific chemokines in response to …

Current researches have determined the significance of C-C chemokine receptor (CCR)6 expression as either a marker of T helper cells (Th) or an effector and regulator of T cell …

2020年10月10日 · In brief, p14 chimeras were generated by transducing congenic B6 mice with a trace population of naïve TCR transgenic CD8 + T cells (p14 T N) specific for the dominant …

2021年2月28日 · Reportedly, mCCL6 (also known as C10) is mainly produced by macrophages 19 and attracts macrophages, CD4 + T cells, and eosinophils. mCCL6 plays important roles in …

2004年2月1日 · In these tissues, CC10/CCL6 is a chemotactic agent for monocytes and macrophages and, to a lesser extent, CD4 + T cells and eosinophils (14, 17, 18). C10/CCL6 …

CCL6 is a chemoattractant for macrophages predominately, although it also recruits B cells, CD4 + T cells, and eosinophils [75–77]. Ccl6 is secreted upon ligation of Tlr4 by fibronectin, an …

2005年10月1日 · In the present study, we investigated the functional expression of CCL6 by rat microglia, which are macrophage-like cells in the CNS and demonstrated that (1) microglia …