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FOXN5 and FOXN6 orthologs share the common domain structure consisting of FN56 and Forhead-box (FOX) domains. Here, we identified and characterized mouse Foxn5 gene by using bioinformatics. Mouse Foxn5, consisting of six exons, was located within mouse genome sequences AC122428.4 and AC125129.5.

Human FOXN5 (292 aa) and rat Foxn5 (296 aa) showed 77.4% total-amino-acid identity. Codon 173-254 of FOXN5 was the Forkhead domain. FOXN5 gene, consisting of six exons, was linked to BCL9L gene at human chromosome 11q23.3.

2004年4月7日 · 前叉箱基因（FOX）通过依赖SHH-GLI途径，TGF-β途径等的转录调控参与胚胎发生，并通过基因扩增，逆转录病毒整合和染色体易位参与癌变。 FOXN1，FOXN2（HTLF），FOXN3（CHES1）和FOXN4构成FOXN家族。 在这里，我们通过使用生物信息学鉴定并表征了FOXN5基因家族的新成员FOXN5基因。 IMAGE5167039（BC028191.1）是源自人FOXN5基因的代表性cDNA。 在大鼠基因组序 …

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