Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and ...

2024年12月25日 · NRF1 (Nuclear Respiratory Factor 1) is a Protein Coding gene. Diseases associated with NRF1 include Oncocytoma and Skin Carcinoma In Situ. Among its related pathways are Cellular responses to stimuli and Transcriptional activation of …

2020年7月23日 · Genetic deletion of Nrf1 prevented regenerating cardiomyocytes from activating a transcriptional program required for heart regeneration. Conversely, Nrf1 overexpression protected the adult...

2023年9月1日 · Multiple lines of evidence demonstrate that the transcription factor NRF1 (NFE2L1) plays crucial roles in proteostasis. NRF1 belongs to the CNC transcription family, which also includes NRF2...

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, …

2025年3月4日 · Title: Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy. Molecular mechanism of specific DNA sequence recognition by NRF1.

2017年11月16日 · Nrf1 is a ubiquitously expressed ER-membrane spanning protein belonging to the Cap’N’Collar (CNC) family of transcription factors that are involved in stress adaptation and detoxification (Sykiotis and Bohmann, 2010).

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation ...

NRF1 (nuclear respiratory factor-1) also known as alpha-palindrome-binding protein is a transcription factor that binds as a homodimer to the DNA sequence motif YGCGCAYGCGCR, where Y and R indicate a pyrimidine (T/C) or purine (A/G) nucleotide.

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, …